Tetranucleotide Microsatellite Mutational Behavior Assessed in Real Time: Implications for Future Microsatellite PanelsSummary

Tetranucleotide Microsatellite Mutational Behavior Assessed in Real Time: Implications for Future Microsatellite PanelsSummary

Background & Aims: Fifty percent of colorectal cancers show elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) and are associated with inflammation, metastasis, and poor patient outcome. EMAST results from interleukin 6–induced nuclear-to-cytosolic displacement of th...

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Bibliographic Details
Main Authors: Maide Ö. Raeker, Jovan Pierre-Charles, John M. Carethers
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
DNA Mismatch Repair
MSH3
Tetranucleotide Microsatellites
Frameshift Mutation
EMAST
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20300126

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