Targeting Mitochondrial and Brain Injury Markers in Acquired Brain Injuries: A Randomized, Double-Blind, Placebo-Controlled Study with Melatonin

Targeting Mitochondrial and Brain Injury Markers in Acquired Brain Injuries: A Randomized, Double-Blind, Placebo-Controlled Study with Melatonin

Purpose: Oxidative stress-induced mitochondrial damage is the main event in acquired brain injuries (ABI). This study aimed to evaluate the effects of melatonin, a mitochondria-targeted antioxidant, on mitochondrial and brain injury markers, and the clinical outcomes of patients with ABI. Methods: I...

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Bibliographic Details
Main Authors: Bahareh Hakiminia, Babak Alikiaie, Fariborz Khorvash, Sarah Mousavi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-01-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
brain injury
melatonin
mitochondria
oxidative stress
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-12-118.pdf

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