Staphylococcus pseudintermedius induces pyroptosis of canine corneal epithelial cells by activating the ROS–NLRP3 signalling pathway

Staphylococcus pseudintermedius induces pyroptosis of canine corneal epithelial cells by activating the ROS–NLRP3 signalling pathway

ABSTRACTStaphylococcus pseudintermedius (S. pseudintermedius) is a common pathogen that causes canine corneal ulcers. However, the pathogenesis remained unclear. In this study, it has been demonstrated that S. pseudintermedius invaded canine corneal epithelial cells (CCECs) intracellularly, mediatin...

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Bibliographic Details
Main Authors: Zhihao Wang, Long Guo, Changning Yuan, Chengcheng Zhu, Jun Li, Haoran Zhong, Peng Mao, Jianji Li, Luying Cui, Junsheng Dong, Kangjun Liu, Xia Meng, Guoqiang Zhu, Heng Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Virulence
Subjects:
Staphylococcus pseudintermedius
canine corneal epithelial cells
intracellular infection
pyroptosis
NLRP3 inflammasome
reactive oxygen species
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2024.2333271

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