Pyrazine and Phenazine Heterocycles: Platforms for Total Synthesis and Drug Discovery

Pyrazine and Phenazine Heterocycles: Platforms for Total Synthesis and Drug Discovery

There are numerous pyrazine and phenazine compounds that demonstrate biological activities relevant to the treatment of disease. In this review, we discuss pyrazine and phenazine agents that have shown potential therapeutic value, including several clinically used agents. In addition, we cover some...

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Bibliographic Details
Main Authors: Robert W. Huigens, Beau R. Brummel, Srinivasarao Tenneti, Aaron T. Garrison, Tao Xiao
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
pyrazine
phenazine
heterocyclic chemistry
total synthesis
medicinal chemistry
Online Access:https://www.mdpi.com/1420-3049/27/3/1112

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