Lipoic acid increases glutathione peroxidase, Na+, K+-ATPase and acetylcholinesterase activities in rat hippocampus after pilocarpine-induced seizures? O ácido lipóico aumenta as atividades da glutationa peroxidase, da Na+, K+-ATPase e da acetilcolinesterase no hipocampo de ratos após convulsões induzidas por pilocarpina?

Lipoic acid increases glutathione peroxidase, Na+, K+-ATPase and acetylcholinesterase activities in rat hippocampus after pilocarpine-induced seizures? O ácido lipóico aumenta as atividades da glutationa peroxidase, da Na+, K+-ATPase e da acetilcolinesterase no hipocampo de ratos após convulsões induzidas por pilocarpina?

In the present study we investigated the effects of lipoic acid (LA) on acetylcholinesterase (AChE), glutathione peroxidase (GPx) and Na+, K+-ATPase activities in rat hippocampus during seizures. Wistar rats were treated with 0.9% saline (i.p., control group), lipoic acid (20 mg/kg, i.p., LA group),...

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Bibliographic Details
Main Authors: Geane Felix de Souza, Gláucio Barros Saldanha, Rivelilson Mendes de Freitas
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2010-08-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
glutationa peroxidase
Na+
K+-ATPase
acetilcolinesterase
convulsões
hipocampo
glutathione peroxidase
acetylcholinesterase
hippocampus
seizures
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000400020

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