Multilayer and MATR3-dependent regulation of mRNAs maintains pluripotency in human induced pluripotent stem cells

Multilayer and MATR3-dependent regulation of mRNAs maintains pluripotency in human induced pluripotent stem cells

Summary: Matrin3 (MATR3) is a nuclear RNA/DNA-binding protein that plays pleiotropic roles in gene expression regulation by directly stabilizing target RNAs and supporting the activity of transcription factors by modulating chromatin architecture. MATR3 is involved in the differentiation of neural c...

Full description

Bibliographic Details
Main Authors: Daniele Pollini, Rosa Loffredo, Federica Maniscalco, Marina Cardano, Mariachiara Micaelli, Isabelle Bonomo, Nausicaa Valentina Licata, Daniele Peroni, Weronika Tomaszewska, Annalisa Rossi, Valeria Crippa, Erik Dassi, Gabriella Viero, Alessandro Quattrone, Angelo Poletti, Luciano Conti, Alessandro Provenzani
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
molecular biology
cellular neuroscience
stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001656

Similar Items

Similar Items