Quantitative Brain MRI Metrics Distinguish Four Different ALS Phenotypes: A Machine Learning Based Study

Quantitative Brain MRI Metrics Distinguish Four Different ALS Phenotypes: A Machine Learning Based Study

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease whose diagnosis depends on the presence of combined lower motor neuron (LMN) and upper motor neuron (UMN) degeneration. LMN degeneration assessment is aided by electromyography, whereas no equivalent exists to assess UMN dysfun...

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Bibliographic Details
Main Authors: Venkateswaran Rajagopalan, Krishna G. Chaitanya, Erik P. Pioro
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Diagnostics
Subjects:
ALS phenotypes
MRI
machine learning
Random Forest
neural network
Online Access:https://www.mdpi.com/2075-4418/13/9/1521

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