Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function
Background: To investigate physical fitness as a mediator of the relationship between arterial stiffness and cognitive function in seniors. Methods: This is a cross-sectional study comprising 155 individuals free from chronic diseases (75.5 ± 6.5 years; 69.7% female). Carotid-femoral pulse wave was...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-12-01
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| Series: | Artery Research |
| Subjects: | |
| Online Access: | https://www.atlantis-press.com/article/125924843/view |
| _version_ | 1811302317405765632 |
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| author | Alinne Nascimento Duarte Barros José Oliveira Joana Carvalho Lucimere Bohn |
| author_facet | Alinne Nascimento Duarte Barros José Oliveira Joana Carvalho Lucimere Bohn |
| author_sort | Alinne Nascimento |
| collection | DOAJ |
| description | Background: To investigate physical fitness as a mediator of the relationship between arterial stiffness and cognitive function in seniors.
Methods: This is a cross-sectional study comprising 155 individuals free from chronic diseases (75.5 ± 6.5 years; 69.7% female). Carotid-femoral pulse wave was assessed through applanation tonometry. Cognitive function was evaluated with Montreal Cognitive Assessment (MoCA). Physical fitness was assessed through handgrip strength and Senior Fitness Test (SFT). A Z-score including individual physical fitness components was computed as a global index of physical fitness. Hayes’s PROCESS macro for Statistical Package for the Social Sciences was used for the simple mediation analysis, using bootstrapped procedures.
Results: After adjustments for sex and age, physical fitness Z-score mediated the relationship between arterial stiffness and cognitive function [Indirect effect = −0.382 (95% CI −0.670 to −0.138)].
Conclusion: Findings suggest that physical fitness, independently of sex and age, is a mediator on the relationship between arterial stiffness and cognitive function in seniors free from chronic diseases. |
| first_indexed | 2024-04-13T07:27:14Z |
| format | Article |
| id | doaj.art-9fcffee0409b4841b361ef904eed55c9 |
| institution | Directory Open Access Journal |
| issn | 1876-4401 |
| language | English |
| last_indexed | 2024-04-13T07:27:14Z |
| publishDate | 2019-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Artery Research |
| spelling | doaj.art-9fcffee0409b4841b361ef904eed55c92022-12-22T02:56:28ZengBMCArtery Research1876-44012019-12-0125310.2991/artres.k.191121.001Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive FunctionAlinne NascimentoDuarte BarrosJosé OliveiraJoana CarvalhoLucimere BohnBackground: To investigate physical fitness as a mediator of the relationship between arterial stiffness and cognitive function in seniors. Methods: This is a cross-sectional study comprising 155 individuals free from chronic diseases (75.5 ± 6.5 years; 69.7% female). Carotid-femoral pulse wave was assessed through applanation tonometry. Cognitive function was evaluated with Montreal Cognitive Assessment (MoCA). Physical fitness was assessed through handgrip strength and Senior Fitness Test (SFT). A Z-score including individual physical fitness components was computed as a global index of physical fitness. Hayes’s PROCESS macro for Statistical Package for the Social Sciences was used for the simple mediation analysis, using bootstrapped procedures. Results: After adjustments for sex and age, physical fitness Z-score mediated the relationship between arterial stiffness and cognitive function [Indirect effect = −0.382 (95% CI −0.670 to −0.138)]. Conclusion: Findings suggest that physical fitness, independently of sex and age, is a mediator on the relationship between arterial stiffness and cognitive function in seniors free from chronic diseases.https://www.atlantis-press.com/article/125924843/viewPhysical fitnessarterial stiffnesscognitionelderspulse wave velocity |
| spellingShingle | Alinne Nascimento Duarte Barros José Oliveira Joana Carvalho Lucimere Bohn Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function Artery Research Physical fitness arterial stiffness cognition elders pulse wave velocity |
| title | Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function |
| title_full | Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function |
| title_fullStr | Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function |
| title_full_unstemmed | Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function |
| title_short | Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function |
| title_sort | physical fitness is a mediator in the relationship between arterial stiffness and cognitive function |
| topic | Physical fitness arterial stiffness cognition elders pulse wave velocity |
| url | https://www.atlantis-press.com/article/125924843/view |
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