A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
With one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities. The World Health Organization (WHO) recommends that individualized assessments be conducted before any vaccine introd...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/7/10/458 |
| _version_ | 1818303976285667328 |
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| author | Elizabeth McMahon Liliana Encinales Carlos Navarro Encinales Silvana Vielma Nelly Pacheco Lil Geraldine Avendaño Echavez Sandra Acosta Rodríguez Milena Calderon Silvia Encinales Sanabria Lorena Encinales Sanabria Ericka Serrano Bernal Andrés Gonzaléz Coba Dennys Jiménez Gary Simon Aileen Y. Chang |
| author_facet | Elizabeth McMahon Liliana Encinales Carlos Navarro Encinales Silvana Vielma Nelly Pacheco Lil Geraldine Avendaño Echavez Sandra Acosta Rodríguez Milena Calderon Silvia Encinales Sanabria Lorena Encinales Sanabria Ericka Serrano Bernal Andrés Gonzaléz Coba Dennys Jiménez Gary Simon Aileen Y. Chang |
| author_sort | Elizabeth McMahon |
| collection | DOAJ |
| description | With one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities. The World Health Organization (WHO) recommends that individualized assessments be conducted before any vaccine introduction to evaluate disease burden and the strength of current vaccination programs. This study seeks to aid in that decision-making process by examining the acceptability and feasibility of dengue vaccine introduction in Barranquilla, Colombia, and Merida, Venezuela. Surveys were administered February−June of 2018 for three groups: patients (<i>n</i> = 351), health professionals (<i>n</i> = 197), and government officials (<i>n</i> = 26). In Barranquilla, most respondents reported dengue to be a moderate-severe problem, that a dengue vaccine would be useful in their communities, and that their current vaccination programs could handle the addition of a new vaccine. In Venezuela, respondents were less likely to view dengue as a major concern and listed multiple barriers to not just dengue vaccine introduction, but to providing current vaccines as well. Further work is needed in Colombia to more objectively assess the country’s readiness as a whole for a future dengue vaccine. As political and social unrest continues in Venezuela, however, future initiatives should focus on trust and capacity building. This study can serve as a framework for future assessments of the acceptability and feasibility of a dengue vaccine in both targeted areas and on larger scales. |
| first_indexed | 2024-12-13T06:03:21Z |
| format | Article |
| id | doaj.art-9fd13e0cb3834152b281a58d21f32b51 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-12-13T06:03:21Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-9fd13e0cb3834152b281a58d21f32b512022-12-21T23:57:17ZengMDPI AGMicroorganisms2076-26072019-10-0171045810.3390/microorganisms7100458microorganisms7100458A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, VenezuelaElizabeth McMahon0Liliana Encinales1Carlos Navarro Encinales2Silvana Vielma3Nelly Pacheco4Lil Geraldine Avendaño Echavez5Sandra Acosta Rodríguez6Milena Calderon7Silvia Encinales Sanabria8Lorena Encinales Sanabria9Ericka Serrano Bernal10Andrés Gonzaléz Coba11Dennys Jiménez12Gary Simon13Aileen Y. Chang14Department of Medicine, The George Washington University, Washington, DC 20037, USAAllied Research Society, LLC, Barranquilla, Atlántico 080001, ColombiaFundación Hospital Universitario Metropolitano, Barranquilla, Atlántico 080001, ColombiaDepartament of clinical microbiology and parasitology, Universidad de los Andes, Merida, Estado Merida 5101, VenezuelaAllied Research Society, LLC, Barranquilla, Atlántico 080001, ColombiaDepartment of Internal Medicine, Universidad Simón Bolívar, Barranquilla, Atlántico 080002, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaClinica de La Costa LTDA, Barranquilla, Atlántico 080001, ColombiaDepartment of Medicine, The George Washington University, Washington, DC 20037, USADepartment of Medicine, The George Washington University, Washington, DC 20037, USAWith one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities. The World Health Organization (WHO) recommends that individualized assessments be conducted before any vaccine introduction to evaluate disease burden and the strength of current vaccination programs. This study seeks to aid in that decision-making process by examining the acceptability and feasibility of dengue vaccine introduction in Barranquilla, Colombia, and Merida, Venezuela. Surveys were administered February−June of 2018 for three groups: patients (<i>n</i> = 351), health professionals (<i>n</i> = 197), and government officials (<i>n</i> = 26). In Barranquilla, most respondents reported dengue to be a moderate-severe problem, that a dengue vaccine would be useful in their communities, and that their current vaccination programs could handle the addition of a new vaccine. In Venezuela, respondents were less likely to view dengue as a major concern and listed multiple barriers to not just dengue vaccine introduction, but to providing current vaccines as well. Further work is needed in Colombia to more objectively assess the country’s readiness as a whole for a future dengue vaccine. As political and social unrest continues in Venezuela, however, future initiatives should focus on trust and capacity building. This study can serve as a framework for future assessments of the acceptability and feasibility of a dengue vaccine in both targeted areas and on larger scales.https://www.mdpi.com/2076-2607/7/10/458dengue vaccinesfeasibility studiescolombiavenezuela |
| spellingShingle | Elizabeth McMahon Liliana Encinales Carlos Navarro Encinales Silvana Vielma Nelly Pacheco Lil Geraldine Avendaño Echavez Sandra Acosta Rodríguez Milena Calderon Silvia Encinales Sanabria Lorena Encinales Sanabria Ericka Serrano Bernal Andrés Gonzaléz Coba Dennys Jiménez Gary Simon Aileen Y. Chang A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela Microorganisms dengue vaccines feasibility studies colombia venezuela |
| title | A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela |
| title_full | A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela |
| title_fullStr | A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela |
| title_full_unstemmed | A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela |
| title_short | A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela |
| title_sort | dengue vaccine will it be accepted and is it feasible lessons from barranquilla colombia and merida venezuela |
| topic | dengue vaccines feasibility studies colombia venezuela |
| url | https://www.mdpi.com/2076-2607/7/10/458 |
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