A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION
The main risk factors of oral/oropharyngeal carcinomas (OPCs) are smoking and alcohol. Recently, another risk factor has been identified: Human Papilloma Virus (HPV). This study is aimed to define demographic and clinical data of OPC in western Sicilian native population and their correlation with H...
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| Format: | Article |
| Language: | English |
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Associazione Italiana Giovani Medici
2022-10-01
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| Series: | Euromediterranean Biomedical Journal |
| Subjects: | |
| Online Access: | http://www.embj.org/wp-content/uploads/2022/10/Verro_31.pdf |
| _version_ | 1797990811401453568 |
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| author | Barbara Verro |
| author_facet | Barbara Verro |
| author_sort | Barbara Verro |
| collection | DOAJ |
| description | The main risk factors of oral/oropharyngeal carcinomas (OPCs) are smoking and alcohol. Recently, another risk factor has been identified: Human Papilloma Virus (HPV). This study is aimed to define demographic and clinical data of OPC in western Sicilian native population and their correlation with HPV. A retrospective study was carried out on 112 patients with OPC: 66.96% were males and 55.36% were over 65; 75% smoked more than 20 cigarettes/day; 64.28% did not drink alcohol. HPV was detected in 48/112 patients: 54.17% were females and 41.67% were under 65; the most affected subsite was palatine tonsil. Statistically significant association between age (over 65), gender (female), anatomical subsite (palatine tonsil) and HPV-related carcinoma was found. Our study confirmed a significant diffusion of OPCs in western Sicilian population and the crucial role of HPV. In our opinion, it’s mandatory to search for HPV in biopsy sample to schedule the best therapeutic protocol. |
| first_indexed | 2024-04-11T08:42:12Z |
| format | Article |
| id | doaj.art-9fd15e56d4764b1dace7bab44866c2cf |
| institution | Directory Open Access Journal |
| issn | 2279-7165 |
| language | English |
| last_indexed | 2024-04-11T08:42:12Z |
| publishDate | 2022-10-01 |
| publisher | Associazione Italiana Giovani Medici |
| record_format | Article |
| series | Euromediterranean Biomedical Journal |
| spelling | doaj.art-9fd15e56d4764b1dace7bab44866c2cf2022-12-22T04:34:11ZengAssociazione Italiana Giovani MediciEuromediterranean Biomedical Journal2279-71652022-10-01173114815110.3269/1970-5492.2022.17.31A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATIONBarbara Verro0https://orcid.org/0000-0002-1940-5281University Hospital of PalermoThe main risk factors of oral/oropharyngeal carcinomas (OPCs) are smoking and alcohol. Recently, another risk factor has been identified: Human Papilloma Virus (HPV). This study is aimed to define demographic and clinical data of OPC in western Sicilian native population and their correlation with HPV. A retrospective study was carried out on 112 patients with OPC: 66.96% were males and 55.36% were over 65; 75% smoked more than 20 cigarettes/day; 64.28% did not drink alcohol. HPV was detected in 48/112 patients: 54.17% were females and 41.67% were under 65; the most affected subsite was palatine tonsil. Statistically significant association between age (over 65), gender (female), anatomical subsite (palatine tonsil) and HPV-related carcinoma was found. Our study confirmed a significant diffusion of OPCs in western Sicilian population and the crucial role of HPV. In our opinion, it’s mandatory to search for HPV in biopsy sample to schedule the best therapeutic protocol. http://www.embj.org/wp-content/uploads/2022/10/Verro_31.pdforal canceroropharynx cancerpapillomasquamous cellhead and neck squamous cell carcinomas |
| spellingShingle | Barbara Verro A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION Euromediterranean Biomedical Journal oral cancer oropharynx cancer papilloma squamous cell head and neck squamous cell carcinomas |
| title | A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION |
| title_full | A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION |
| title_fullStr | A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION |
| title_full_unstemmed | A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION |
| title_short | A RETROSPECTIVE STUDY OF ORAL AND OROPHARYNGEAL CARCINOMA IN THE WESTERN SICILY POPULATION |
| title_sort | retrospective study of oral and oropharyngeal carcinoma in the western sicily population |
| topic | oral cancer oropharynx cancer papilloma squamous cell head and neck squamous cell carcinomas |
| url | http://www.embj.org/wp-content/uploads/2022/10/Verro_31.pdf |
| work_keys_str_mv | AT barbaraverro aretrospectivestudyoforalandoropharyngealcarcinomainthewesternsicilypopulation AT barbaraverro retrospectivestudyoforalandoropharyngealcarcinomainthewesternsicilypopulation |