Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison
Background: This study investigates changes in cognitive function in patients with severe carotid stenosis who underwent carotid endarterectomy (CEA) and carotid stenting (CAS) over two decades. Methods: We compared cognitive function within 30 days after the procedure in 267 patients (first 100 eac...
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| Format: | Article |
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MDPI AG
2023-12-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/12/1/13 |
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| author | Daniel Václavík David Pakizer Tomáš Hrbáč Martin Roubec Václav Procházka Tomáš Jonszta Roman Herzig David Školoudík |
| author_facet | Daniel Václavík David Pakizer Tomáš Hrbáč Martin Roubec Václav Procházka Tomáš Jonszta Roman Herzig David Školoudík |
| author_sort | Daniel Václavík |
| collection | DOAJ |
| description | Background: This study investigates changes in cognitive function in patients with severe carotid stenosis who underwent carotid endarterectomy (CEA) and carotid stenting (CAS) over two decades. Methods: We compared cognitive function within 30 days after the procedure in 267 patients (first 100 each for CEA and CAS in two periods: 2008–2012 and 2018–2022) in a single institution. Assessments used Adenbrooke’s Cognitive Examination–Revised (ACE-R), the Mini-Mental State Examination (MMSE), Speech Fluency Test (SFT), and Clock Drawing Test (CDT), conducted before and 30 ± 2 days after surgery. Results: Patients (mean age 67.2 years, 70%+ carotid stenosis) exhibited different cognitive changes over periods. In 2008–2012, significant declines in MMSE (CEA, <i>p</i> = 0.049) and CDT (CAS, <i>p</i> = 0.015) were observed among asymptomatic patients. On the contrary, in 2018–2022, improvements were observed in ACE-R and MMSE for symptomatic and asymptomatic patients undergoing CEA and CAS. Conclusion: Over a decade, advances in interventional techniques and patient management have reduced risks of cognitive decline in patients with asymptomatic carotid stenosis and also have improved cognitive functions in both symptomatic and asymptomatic individuals. |
| first_indexed | 2024-03-08T09:58:01Z |
| format | Article |
| id | doaj.art-9fd64ed4efcb48dfabb4a56362fa3086 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-08T09:58:01Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-9fd64ed4efcb48dfabb4a56362fa30862024-01-29T13:46:28ZengMDPI AGBiomedicines2227-90592023-12-011211310.3390/biomedicines12010013Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart ComparisonDaniel Václavík0David Pakizer1Tomáš Hrbáč2Martin Roubec3Václav Procházka4Tomáš Jonszta5Roman Herzig6David Školoudík7Department of Neurology, University Hospital Ostrava, 708 00 Ostrava, Czech RepublicCentre for Health Research, Faculty of Medicine, University of Ostrava, Syllabova 19, 703 00 Ostrava, Czech RepublicDepartment of Neurosurgery, University Hospital Ostrava, 708 52 Ostrava, Czech RepublicDepartment of Neurology, University Hospital Ostrava, 708 00 Ostrava, Czech RepublicDepartment of Radiodiagnostics, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, 703 00 Ostrava, Czech RepublicDepartment of Radiodiagnostics, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, 703 00 Ostrava, Czech RepublicComprehensive Stroke Centre, Department of Neurology, Charles University Faculty of Medicine and University Hospital, 500 05 Hradec Králové, Czech RepublicDepartment of Neurology, University Hospital Ostrava, 708 00 Ostrava, Czech RepublicBackground: This study investigates changes in cognitive function in patients with severe carotid stenosis who underwent carotid endarterectomy (CEA) and carotid stenting (CAS) over two decades. Methods: We compared cognitive function within 30 days after the procedure in 267 patients (first 100 each for CEA and CAS in two periods: 2008–2012 and 2018–2022) in a single institution. Assessments used Adenbrooke’s Cognitive Examination–Revised (ACE-R), the Mini-Mental State Examination (MMSE), Speech Fluency Test (SFT), and Clock Drawing Test (CDT), conducted before and 30 ± 2 days after surgery. Results: Patients (mean age 67.2 years, 70%+ carotid stenosis) exhibited different cognitive changes over periods. In 2008–2012, significant declines in MMSE (CEA, <i>p</i> = 0.049) and CDT (CAS, <i>p</i> = 0.015) were observed among asymptomatic patients. On the contrary, in 2018–2022, improvements were observed in ACE-R and MMSE for symptomatic and asymptomatic patients undergoing CEA and CAS. Conclusion: Over a decade, advances in interventional techniques and patient management have reduced risks of cognitive decline in patients with asymptomatic carotid stenosis and also have improved cognitive functions in both symptomatic and asymptomatic individuals.https://www.mdpi.com/2227-9059/12/1/13carotid stenosiscarotid endarterectomy |
| spellingShingle | Daniel Václavík David Pakizer Tomáš Hrbáč Martin Roubec Václav Procházka Tomáš Jonszta Roman Herzig David Školoudík Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison Biomedicines carotid stenosis carotid endarterectomy |
| title | Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison |
| title_full | Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison |
| title_fullStr | Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison |
| title_full_unstemmed | Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison |
| title_short | Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison |
| title_sort | changes in cognitive functions after carotid endarterectomy and carotid stenting a decade apart comparison |
| topic | carotid stenosis carotid endarterectomy |
| url | https://www.mdpi.com/2227-9059/12/1/13 |
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