Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions
Asymmetric organocatalytic aldol condensation is discussed on the basis of intramolecular and inter-molecular reactions. In addition to the widely used proline and its derivatives an application of the new type of the organocatalyst – bimorpholines in the above-mentioned reactions is descr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
2007-05-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://chimia.ch/chimia/article/view/4317 |
| _version_ | 1811320341064056832 |
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| author | Kadri Kriis Marju Laars Kristin Lippur Tõnis Kanger |
| author_facet | Kadri Kriis Marju Laars Kristin Lippur Tõnis Kanger |
| author_sort | Kadri Kriis |
| collection | DOAJ |
| description |
Asymmetric organocatalytic aldol condensation is discussed on the basis of intramolecular and inter-molecular reactions. In addition to the widely used proline and its derivatives an application of the new type of the organocatalyst – bimorpholines in the above-mentioned reactions
is described. The new catalyst has a unique C2-symmetric skeleton with four acceptor sites that makes it stereoselective and efficient. Small changes in the structure of the catalyst lead to a remarkable loss of selectivity.
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| first_indexed | 2024-04-13T12:57:47Z |
| format | Article |
| id | doaj.art-9fd7c1f413da4d58bc8ae00d3bf32832 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-04-13T12:57:47Z |
| publishDate | 2007-05-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-9fd7c1f413da4d58bc8ae00d3bf328322022-12-22T02:46:00ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242007-05-0161510.2533/chimia.2007.232Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol ReactionsKadri KriisMarju LaarsKristin LippurTõnis Kanger Asymmetric organocatalytic aldol condensation is discussed on the basis of intramolecular and inter-molecular reactions. In addition to the widely used proline and its derivatives an application of the new type of the organocatalyst – bimorpholines in the above-mentioned reactions is described. The new catalyst has a unique C2-symmetric skeleton with four acceptor sites that makes it stereoselective and efficient. Small changes in the structure of the catalyst lead to a remarkable loss of selectivity. https://chimia.ch/chimia/article/view/4317Aldol condensationBimorpholineOrganocatalysisStereoselective |
| spellingShingle | Kadri Kriis Marju Laars Kristin Lippur Tõnis Kanger Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions CHIMIA Aldol condensation Bimorpholine Organocatalysis Stereoselective |
| title | Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions |
| title_full | Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions |
| title_fullStr | Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions |
| title_full_unstemmed | Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions |
| title_short | Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions |
| title_sort | bimorpholines as alternative organocatalysts in asymmetric aldol reactions |
| topic | Aldol condensation Bimorpholine Organocatalysis Stereoselective |
| url | https://chimia.ch/chimia/article/view/4317 |
| work_keys_str_mv | AT kadrikriis bimorpholinesasalternativeorganocatalystsinasymmetricaldolreactions AT marjulaars bimorpholinesasalternativeorganocatalystsinasymmetricaldolreactions AT kristinlippur bimorpholinesasalternativeorganocatalystsinasymmetricaldolreactions AT toniskanger bimorpholinesasalternativeorganocatalystsinasymmetricaldolreactions |