Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population
AbstractMultiparental populations (MPPs) encompass greater genetic diversity than traditional experimental crosses of two inbred strains, enabling broader surveys of genetic variation underlying complex traits. Two such mouse MPPs are the Collaborative Cross (CC) inbred panel and the...
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2023-02-01
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Series: | G3: Genes, Genomes, Genetics |
Online Access: | https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkad027 |