Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery

Background: This study was aimed to compare the effect of nebulized fentanyl versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery. Patients and Methods: A total of sixty patients scheduled for unilateral femur interlock surgery under subarachnoid block wer...

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Main Authors: Jaideep Singh, D Premkumar, Aditya Agarwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Bali Journal of Anesthesiology
Subjects:
Online Access:http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=2;spage=59;epage=61;aulast=Singh
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author Jaideep Singh
D Premkumar
Aditya Agarwal
author_facet Jaideep Singh
D Premkumar
Aditya Agarwal
author_sort Jaideep Singh
collection DOAJ
description Background: This study was aimed to compare the effect of nebulized fentanyl versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery. Patients and Methods: A total of sixty patients scheduled for unilateral femur interlock surgery under subarachnoid block were enrolled in the study and were randomly divided into two groups. Group I included thirty patients who received 2 μg/kg of fentanyl intravenously, and Group N included thirty patients who received 4 μg/kg of fentanyl nebulization using a standard venturi mask. In the postoperative period, whenever the Visual Analog Scale ≥4, patients received the analgesic corresponding to their respective groups. The data obtained were statistically analyzed using IBM SPSS software. Results: There was no significant difference in the demographic characteristics, duration of surgery, the number of patients who required rescue analgesia, and the onset of analgesia in Group N in comparison with Group I. The duration of analgesia was significantly longer in Group N in comparison to Group I. In Group I, the rise in Ramsay sedation score was faster and peaked at 5 min. In Group N, however, it was lesser than that of Group I. Side effects in Group N were significantly lesser compared to Group I. Conclusion: Nebulization with fentanyl is a good alternative to intravenous fentanyl for adequate postoperative pain relief with fewer side effects.
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spelling doaj.art-9fea624c6c6b46d6bb5ec09b2319d58d2022-12-21T22:55:10ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762020-01-0142596110.4103/BJOA.BJOA_14_20Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgeryJaideep SinghD PremkumarAditya AgarwalBackground: This study was aimed to compare the effect of nebulized fentanyl versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery. Patients and Methods: A total of sixty patients scheduled for unilateral femur interlock surgery under subarachnoid block were enrolled in the study and were randomly divided into two groups. Group I included thirty patients who received 2 μg/kg of fentanyl intravenously, and Group N included thirty patients who received 4 μg/kg of fentanyl nebulization using a standard venturi mask. In the postoperative period, whenever the Visual Analog Scale ≥4, patients received the analgesic corresponding to their respective groups. The data obtained were statistically analyzed using IBM SPSS software. Results: There was no significant difference in the demographic characteristics, duration of surgery, the number of patients who required rescue analgesia, and the onset of analgesia in Group N in comparison with Group I. The duration of analgesia was significantly longer in Group N in comparison to Group I. In Group I, the rise in Ramsay sedation score was faster and peaked at 5 min. In Group N, however, it was lesser than that of Group I. Side effects in Group N were significantly lesser compared to Group I. Conclusion: Nebulization with fentanyl is a good alternative to intravenous fentanyl for adequate postoperative pain relief with fewer side effects.http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=2;spage=59;epage=61;aulast=Singhanalgesiafemur interlock surgeryfentanylnebulizedpostoperative
spellingShingle Jaideep Singh
D Premkumar
Aditya Agarwal
Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
Bali Journal of Anesthesiology
analgesia
femur interlock surgery
fentanyl
nebulized
postoperative
title Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
title_full Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
title_fullStr Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
title_full_unstemmed Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
title_short Effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
title_sort effect of nebulized versus intravenous fentanyl for postoperative analgesia after unilateral femur interlock surgery
topic analgesia
femur interlock surgery
fentanyl
nebulized
postoperative
url http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=2;spage=59;epage=61;aulast=Singh
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AT adityaagarwal effectofnebulizedversusintravenousfentanylforpostoperativeanalgesiaafterunilateralfemurinterlocksurgery