On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan
For the first time, the studies of polyhydric alcohols (glycerol, ethylene glycol and propylene glycol) impact on the structure, deformation–strength characteristics and hemocompatibility of the film materials based on chitosan and N-succinyl chitosan were carried out. It was shown that the introduc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina
2022-03-01
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| Series: | Chimica Techno Acta |
| Subjects: | |
| Online Access: | https://journals.urfu.ru/index.php/chimtech/article/view/5677 |
| _version_ | 1818536101259771904 |
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| author | Marina V. Bazunova Roman Yu. Lazdin Mariya R. Elinson Lucia A. Sharafutdinova Robert A. Mustakimov Elena I. Kulish |
| author_facet | Marina V. Bazunova Roman Yu. Lazdin Mariya R. Elinson Lucia A. Sharafutdinova Robert A. Mustakimov Elena I. Kulish |
| author_sort | Marina V. Bazunova |
| collection | DOAJ |
| description | For the first time, the studies of polyhydric alcohols (glycerol, ethylene glycol and propylene glycol) impact on the structure, deformation–strength characteristics and hemocompatibility of the film materials based on chitosan and N-succinyl chitosan were carried out. It was shown that the introduction of polyhydric alcohols into molding solutions during the creation of the films based on chitosan and succinyl chitosan in the amount up to 0.05 mol/l is accompanied by the tensile elongation value increase by 2–2.5 times. The value of the breaking stress in this case decreases by 3–4 times. There is also a decrease in the overall surface roughness and a sharp drop in the elastic modulus of the films. The stabilizing impact of the systems based on chitosan and succinyl chitosan in the presence of glycerol and propylene glycol upon the cell membranes in physiological conditions allows inferring their high hemocompatibility. |
| first_indexed | 2024-12-11T18:33:37Z |
| format | Article |
| id | doaj.art-9fec767a2188478d8f5666c7714f5f90 |
| institution | Directory Open Access Journal |
| issn | 2411-1414 |
| language | English |
| last_indexed | 2024-12-11T18:33:37Z |
| publishDate | 2022-03-01 |
| publisher | Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina |
| record_format | Article |
| series | Chimica Techno Acta |
| spelling | doaj.art-9fec767a2188478d8f5666c7714f5f902022-12-22T00:54:50ZengUralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. ElʹcinaChimica Techno Acta2411-14142022-03-019110.15826/chimtech.2022.9.1.084317On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosanMarina V. Bazunova0Roman Yu. Lazdin1Mariya R. Elinson2Lucia A. Sharafutdinova3Robert A. Mustakimov4Elena I. Kulish5Bashkir State UniversityBashkir State UniversityBashkir State UniversityBashkir State Medical UniversityBashkir State UniversityBashkir State UniversityFor the first time, the studies of polyhydric alcohols (glycerol, ethylene glycol and propylene glycol) impact on the structure, deformation–strength characteristics and hemocompatibility of the film materials based on chitosan and N-succinyl chitosan were carried out. It was shown that the introduction of polyhydric alcohols into molding solutions during the creation of the films based on chitosan and succinyl chitosan in the amount up to 0.05 mol/l is accompanied by the tensile elongation value increase by 2–2.5 times. The value of the breaking stress in this case decreases by 3–4 times. There is also a decrease in the overall surface roughness and a sharp drop in the elastic modulus of the films. The stabilizing impact of the systems based on chitosan and succinyl chitosan in the presence of glycerol and propylene glycol upon the cell membranes in physiological conditions allows inferring their high hemocompatibility.https://journals.urfu.ru/index.php/chimtech/article/view/5677chitosansodium salt of n-succinyl chitosanpolyhydric alcoholsplasticizationdeformation–strength properties |
| spellingShingle | Marina V. Bazunova Roman Yu. Lazdin Mariya R. Elinson Lucia A. Sharafutdinova Robert A. Mustakimov Elena I. Kulish On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan Chimica Techno Acta chitosan sodium salt of n-succinyl chitosan polyhydric alcohols plasticization deformation–strength properties |
| title | On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan |
| title_full | On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan |
| title_fullStr | On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan |
| title_full_unstemmed | On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan |
| title_short | On the possibility of obtaining the elastic and biocompatible film materials based on chitosan and N-succinyl chitosan |
| title_sort | on the possibility of obtaining the elastic and biocompatible film materials based on chitosan and n succinyl chitosan |
| topic | chitosan sodium salt of n-succinyl chitosan polyhydric alcohols plasticization deformation–strength properties |
| url | https://journals.urfu.ru/index.php/chimtech/article/view/5677 |
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