Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella
Abstract Background This study aimed to assess the clinical and hemato-biochemical changes associated with diarrhea in E. coli and Salmonella pathogens in Friesian bovine calves less than one month old as well as to examine the relationship between Vit D3 and cardiac biomarkers. Results The study wa...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-10-01
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| Series: | Beni-Suef University Journal of Basic and Applied Sciences |
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| Online Access: | https://doi.org/10.1186/s43088-022-00309-w |
| _version_ | 1811194777737101312 |
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| author | Ahmed Shehta Heba El-Zahar AbdelKereem Mansour Basma Mustafa Tarek Shety |
| author_facet | Ahmed Shehta Heba El-Zahar AbdelKereem Mansour Basma Mustafa Tarek Shety |
| author_sort | Ahmed Shehta |
| collection | DOAJ |
| description | Abstract Background This study aimed to assess the clinical and hemato-biochemical changes associated with diarrhea in E. coli and Salmonella pathogens in Friesian bovine calves less than one month old as well as to examine the relationship between Vit D3 and cardiac biomarkers. Results The study was carried out on 43 Friesian calves from a private farm in Ash Sharqia Governorate, 33 diarrheic calves aged 1–14 days with an average body weight 43.7 ± 1.2 kg, and 10 apparently healthy calves were kept as a control group to investigate the clinical and hemato-biochemical profiles. E. coli and Salmonella pathogens were isolated from the diarrheic calves where 76% were E. coli and 24% were Salmonella. Diarrheic calves showed signs of anorexia, weakness, dullness, staggering gait, pale mucous membranes with sunken eyes and dehydration. Analysis of clinical and hemato-biochemical profile of the diarrheic calves revealed significant increase in body temperature, respiratory rate, heart rate, white blood cells, neutrophils, serum potassium, urea, creatinine, ALT, AST, cardiac NT-proBNP and cardiac troponin I with significant decrease in hemoglobin, packed cell volume, erythrocytes, serum Vit D3, sodium, glucose, total protein and albumin concentrations. Conclusions It could be concluded that bacterial diarrhea has a severe negative impact on the clinical and hemato-biochemical profile of the neonatal calves with diarrhea. Serum cardiac biomarkers such as cardiac troponin I (cTn-I) and NT-proBNP were significantly higher in neonatal calves with diarrhea, and there is an important relationship between cardiac biomarkers and vitamin D levels. |
| first_indexed | 2024-04-12T00:32:16Z |
| format | Article |
| id | doaj.art-9fee5bf9cae148b29c1bd92e8c01a91c |
| institution | Directory Open Access Journal |
| issn | 2314-8543 |
| language | English |
| last_indexed | 2024-04-12T00:32:16Z |
| publishDate | 2022-10-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Beni-Suef University Journal of Basic and Applied Sciences |
| spelling | doaj.art-9fee5bf9cae148b29c1bd92e8c01a91c2022-12-22T03:55:17ZengSpringerOpenBeni-Suef University Journal of Basic and Applied Sciences2314-85432022-10-011111810.1186/s43088-022-00309-wClinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and SalmonellaAhmed Shehta0Heba El-Zahar1AbdelKereem Mansour2Basma Mustafa3Tarek Shety4Internal Medicine, Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig UniversityInternal Medicine, Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig UniversityInternal Medicine, Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig UniversityInternal Medicine, Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig UniversityInternal Medicine, Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig UniversityAbstract Background This study aimed to assess the clinical and hemato-biochemical changes associated with diarrhea in E. coli and Salmonella pathogens in Friesian bovine calves less than one month old as well as to examine the relationship between Vit D3 and cardiac biomarkers. Results The study was carried out on 43 Friesian calves from a private farm in Ash Sharqia Governorate, 33 diarrheic calves aged 1–14 days with an average body weight 43.7 ± 1.2 kg, and 10 apparently healthy calves were kept as a control group to investigate the clinical and hemato-biochemical profiles. E. coli and Salmonella pathogens were isolated from the diarrheic calves where 76% were E. coli and 24% were Salmonella. Diarrheic calves showed signs of anorexia, weakness, dullness, staggering gait, pale mucous membranes with sunken eyes and dehydration. Analysis of clinical and hemato-biochemical profile of the diarrheic calves revealed significant increase in body temperature, respiratory rate, heart rate, white blood cells, neutrophils, serum potassium, urea, creatinine, ALT, AST, cardiac NT-proBNP and cardiac troponin I with significant decrease in hemoglobin, packed cell volume, erythrocytes, serum Vit D3, sodium, glucose, total protein and albumin concentrations. Conclusions It could be concluded that bacterial diarrhea has a severe negative impact on the clinical and hemato-biochemical profile of the neonatal calves with diarrhea. Serum cardiac biomarkers such as cardiac troponin I (cTn-I) and NT-proBNP were significantly higher in neonatal calves with diarrhea, and there is an important relationship between cardiac biomarkers and vitamin D levels.https://doi.org/10.1186/s43088-022-00309-wBovine calvesDiarrheaHemato-biochemicalVit D3Cardiac biomarkers |
| spellingShingle | Ahmed Shehta Heba El-Zahar AbdelKereem Mansour Basma Mustafa Tarek Shety Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella Beni-Suef University Journal of Basic and Applied Sciences Bovine calves Diarrhea Hemato-biochemical Vit D3 Cardiac biomarkers |
| title | Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella |
| title_full | Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella |
| title_fullStr | Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella |
| title_full_unstemmed | Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella |
| title_short | Clinical, hematological and some biochemical alterations during diarrhea in Friesian calves naturally infected with E. coli and Salmonella |
| title_sort | clinical hematological and some biochemical alterations during diarrhea in friesian calves naturally infected with e coli and salmonella |
| topic | Bovine calves Diarrhea Hemato-biochemical Vit D3 Cardiac biomarkers |
| url | https://doi.org/10.1186/s43088-022-00309-w |
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