In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma Production

In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma Production

Increased rates of indeterminate QuantiFERON-TB Gold Plus Assay (QFT-Plus) were demonstrated in patients hospitalized with Coronavirus Disease (COVID)-19. We aimed to define the prevalence and characteristics of hospitalized COVID-19 patients with indeterminate QFT-Plus. A retrospective study was pe...

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Bibliographic Details
Main Authors: Alessandra Imeneo, Grazia Alessio, Andrea Di Lorenzo, Laura Campogiani, Alessandra Lodi, Filippo Barreca, Marta Zordan, Virginia Barchi, Barbara Massa, Simona Tedde, Angela Crea, Pietro Vitale, Ilaria Spalliera, Mirko Compagno, Luigi Coppola, Luca Dori, Vincenzo Malagnino, Elisabetta Teti, Massimo Andreoni, Loredana Sarmati, Marco Iannetta
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Life
Subjects:
QuantiFERON-TB Gold
IGRA
SARS-CoV-2
CD3
lymphopenia
IFN
Online Access:https://www.mdpi.com/2075-1729/12/2/244

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