Sphingosine-1-Phosphate: Its Pharmacological Regulation and the Treatment of Multiple Sclerosis: A Review Article

Sphingosine-1-Phosphate: Its Pharmacological Regulation and the Treatment of Multiple Sclerosis: A Review Article

Sphingosine-1-phosphate (S1P), via its G-protein-coupled receptors, is a signaling molecule with important regulatory properties on numerous, widely varied cell types. Five S1P receptors (S1PR1-5) have been identified, each with effects determined by their unique G-protein-driven downstream pathways...

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Bibliographic Details
Main Authors: Stanley Cohan, Elisabeth Lucassen, Kyle Smoot, Justine Brink, Chiayi Chen
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomedicines
Subjects:
multiple sclerosis
sphingosine-1-phosphate modulators
Online Access:https://www.mdpi.com/2227-9059/8/7/227

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