Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices

Abstract Background To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM). Methods Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through n...

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Main Authors: André Rosentreter, Alexandra Lappas, Randolf Alexander Widder, Maged Alnawaiseh, Thomas Stefan Dietlein
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-018-0721-6
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author André Rosentreter
Alexandra Lappas
Randolf Alexander Widder
Maged Alnawaiseh
Thomas Stefan Dietlein
author_facet André Rosentreter
Alexandra Lappas
Randolf Alexander Widder
Maged Alnawaiseh
Thomas Stefan Dietlein
author_sort André Rosentreter
collection DOAJ
description Abstract Background To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM). Methods Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through necrosis of the overlying scleral flap and conjunctiva after Baerveldt drainage device surgery. The defects were repaired by lateral displacement of the tube towards the sclera, with a slice of a CGM as a patch, covered by adjacent conjunctiva. Result Successful, lasting closure (follow-up of 12 to 42 months) of the conjunctival defects was achieved without any side-effects or complications in all eight cases. Conclusions Erosion of the drainage tube, creating buttonholes in the conjunctiva after implantation of glaucoma drainage devices, is a potentially serious problem. It can be managed successfully using a biodegradable CGM as a patch.
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spelling doaj.art-9ff9c61cc3b24f22adeb4447669df49f2022-12-22T01:58:29ZengBMCBMC Ophthalmology1471-24152018-02-011811510.1186/s12886-018-0721-6Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matricesAndré Rosentreter0Alexandra Lappas1Randolf Alexander Widder2Maged Alnawaiseh3Thomas Stefan Dietlein4Department of Ophthalmology, University of WürzburgCenter of Ophthalmology, University of CologneDepartment of Ophthalmology, St. Martinus-Krankenhaus DüsseldorfDepartment Of Ophthalmology, University of Muenster Medical CenterCenter of Ophthalmology, University of CologneAbstract Background To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM). Methods Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through necrosis of the overlying scleral flap and conjunctiva after Baerveldt drainage device surgery. The defects were repaired by lateral displacement of the tube towards the sclera, with a slice of a CGM as a patch, covered by adjacent conjunctiva. Result Successful, lasting closure (follow-up of 12 to 42 months) of the conjunctival defects was achieved without any side-effects or complications in all eight cases. Conclusions Erosion of the drainage tube, creating buttonholes in the conjunctiva after implantation of glaucoma drainage devices, is a potentially serious problem. It can be managed successfully using a biodegradable CGM as a patch.http://link.springer.com/article/10.1186/s12886-018-0721-6Episcleral drainage deviceBaerveldtAhmedCollagen-glycosaminoglycane matrix (CGM)Drainage tubeConjunctival defect
spellingShingle André Rosentreter
Alexandra Lappas
Randolf Alexander Widder
Maged Alnawaiseh
Thomas Stefan Dietlein
Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
BMC Ophthalmology
Episcleral drainage device
Baerveldt
Ahmed
Collagen-glycosaminoglycane matrix (CGM)
Drainage tube
Conjunctival defect
title Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_full Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_fullStr Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_full_unstemmed Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_short Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_sort conjunctival repair after glaucoma drainage device exposure using collagen glycosaminoglycane matrices
topic Episcleral drainage device
Baerveldt
Ahmed
Collagen-glycosaminoglycane matrix (CGM)
Drainage tube
Conjunctival defect
url http://link.springer.com/article/10.1186/s12886-018-0721-6
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