Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study
Abstract Background This study aimed to investigate the prescription of traditional herbal medicines for the treatment of unexplained female infertility in Korea. By analyzing the relationships among the prescriptions and between the prescriptions and treatment outcomes, we aimed to confirm the util...
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Complementary Medicine and Therapies |
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| Online Access: | https://doi.org/10.1186/s12906-023-04192-5 |
| _version_ | 1797578191007645696 |
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| author | Su-Ji Choi Dong-Il Kim |
| author_facet | Su-Ji Choi Dong-Il Kim |
| author_sort | Su-Ji Choi |
| collection | DOAJ |
| description | Abstract Background This study aimed to investigate the prescription of traditional herbal medicines for the treatment of unexplained female infertility in Korea. By analyzing the relationships among the prescriptions and between the prescriptions and treatment outcomes, we aimed to confirm the utilization of standardized prescriptions and the effectiveness of this standardization. Methods The data were derived from the “support projects” of the local government for infertile women to receive Korean medical treatments. The presciption data of 453 participants from 2017 to 2018 were analyzed. Data preprocessing, frequency analysis, and network analysis were conducted. For network analysis, the characteristics of the herbal medicine prescriptions were used to calculate the degree centrality, closeness centrality and eigenvector centrality. Modularity clustering was also performed for cluster analysis. Results Fifty different prescriptions were used, among which only 22 were used for participants who became pregnant. The recommended standard prescriptions for support projects were used frequently. “BaeranChacksangBang” showed the highest level of in-degree centrality. Among the prescriptions for participants who became pregnant, “JogyeongJongokTang” and “BaeranChacksangBang” were the most influential nodes. “BaeranChacksangBang”, “AnjeonYicheonTang”, “YukLinZu” and “JogyeongJongokTang” had high closeness centrality among the prescriptions for participants who became pregnant. Clustering analysis of the prescriptions for participants who became pregnant revealed that the prescriptions showed the best modularity when divided into five groups. Conclusions These findings depict the utilization of Korean herbal medicine in the real world and the dynamics underlying the herbal medicine prescription patterns for infertile women. |
| first_indexed | 2024-03-10T22:19:33Z |
| format | Article |
| id | doaj.art-9ffae3eaff91453e87c16850d70c5550 |
| institution | Directory Open Access Journal |
| issn | 2662-7671 |
| language | English |
| last_indexed | 2024-03-10T22:19:33Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary Medicine and Therapies |
| spelling | doaj.art-9ffae3eaff91453e87c16850d70c55502023-11-19T12:21:01ZengBMCBMC Complementary Medicine and Therapies2662-76712023-10-0123111310.1186/s12906-023-04192-5Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective studySu-Ji Choi0Dong-Il Kim1Department of Obstetrics and Gynecology, College of Korean Medicine, Dong-eui UniversityDepartment of Obstetrics and Gynecology, College of Korean Medicine, Dongguk UniversityAbstract Background This study aimed to investigate the prescription of traditional herbal medicines for the treatment of unexplained female infertility in Korea. By analyzing the relationships among the prescriptions and between the prescriptions and treatment outcomes, we aimed to confirm the utilization of standardized prescriptions and the effectiveness of this standardization. Methods The data were derived from the “support projects” of the local government for infertile women to receive Korean medical treatments. The presciption data of 453 participants from 2017 to 2018 were analyzed. Data preprocessing, frequency analysis, and network analysis were conducted. For network analysis, the characteristics of the herbal medicine prescriptions were used to calculate the degree centrality, closeness centrality and eigenvector centrality. Modularity clustering was also performed for cluster analysis. Results Fifty different prescriptions were used, among which only 22 were used for participants who became pregnant. The recommended standard prescriptions for support projects were used frequently. “BaeranChacksangBang” showed the highest level of in-degree centrality. Among the prescriptions for participants who became pregnant, “JogyeongJongokTang” and “BaeranChacksangBang” were the most influential nodes. “BaeranChacksangBang”, “AnjeonYicheonTang”, “YukLinZu” and “JogyeongJongokTang” had high closeness centrality among the prescriptions for participants who became pregnant. Clustering analysis of the prescriptions for participants who became pregnant revealed that the prescriptions showed the best modularity when divided into five groups. Conclusions These findings depict the utilization of Korean herbal medicine in the real world and the dynamics underlying the herbal medicine prescription patterns for infertile women.https://doi.org/10.1186/s12906-023-04192-5InfertilitySubfertilityHerbal medicineUnexplained infertilityTraditional East Asian medicinePregnancy |
| spellingShingle | Su-Ji Choi Dong-Il Kim Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study BMC Complementary Medicine and Therapies Infertility Subfertility Herbal medicine Unexplained infertility Traditional East Asian medicine Pregnancy |
| title | Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study |
| title_full | Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study |
| title_fullStr | Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study |
| title_full_unstemmed | Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study |
| title_short | Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study |
| title_sort | utilization of traditional herbal medicine formulas for unexplained female infertility in korea a retrospective study |
| topic | Infertility Subfertility Herbal medicine Unexplained infertility Traditional East Asian medicine Pregnancy |
| url | https://doi.org/10.1186/s12906-023-04192-5 |
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