Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients

Circularized transcript isoforms due to back-splicing are increasingly being reported in different tissues types and pathological states including cancer. Since these circular RNAs (circRNAs) are more stable than linear messenger RNA their identification and profiling in tumor tissue could aid in st...

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Détails bibliographiques
Auteurs principaux: Anshita Goel, Douglas G. Ward, Naheema S. Gordon, Ben Abbotts, Maurice P. Zeegers, K. K. Cheng, Nicholas D. James, Richard T. Bryan, Roland Arnold
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2020-05-01
Collection:Frontiers in Oncology
Sujets:
Accès en ligne:https://www.frontiersin.org/article/10.3389/fonc.2020.00812/full