Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients

Circularized transcript isoforms due to back-splicing are increasingly being reported in different tissues types and pathological states including cancer. Since these circular RNAs (circRNAs) are more stable than linear messenger RNA their identification and profiling in tumor tissue could aid in st...

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Main Authors: Anshita Goel, Douglas G. Ward, Naheema S. Gordon, Ben Abbotts, Maurice P. Zeegers, K. K. Cheng, Nicholas D. James, Richard T. Bryan, Roland Arnold
格式: 文件
语言:English
出版: Frontiers Media S.A. 2020-05-01
丛编:Frontiers in Oncology
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在线阅读:https://www.frontiersin.org/article/10.3389/fonc.2020.00812/full