Plasma cell vulvitis: A case report
Plasma cell vulvitis (PCV) is a rare inflammatory condition characterised by plasma cell infiltration in the vulva. A woman in her 80s was referred to a specialist gynaecology clinic with chronic, painful vulval ulcers that were non-responsive to topical betamethasone. Following a biopsy confirming...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Case Reports in Women's Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214911224000225 |
| _version_ | 1797234056982691840 |
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| author | Lauren Fisher Eman Alnaggar |
| author_facet | Lauren Fisher Eman Alnaggar |
| author_sort | Lauren Fisher |
| collection | DOAJ |
| description | Plasma cell vulvitis (PCV) is a rare inflammatory condition characterised by plasma cell infiltration in the vulva. A woman in her 80s was referred to a specialist gynaecology clinic with chronic, painful vulval ulcers that were non-responsive to topical betamethasone. Following a biopsy confirming PCV, combination therapy was initiated. This included non-pharmacological management, such as promoting aeration and using hypoallergenic clothing and washes, combined with the daily application of clobetasone cream 0.05% and clindamycin cream 0.1%. Additionally, topical estriol 1% was applied twice weekly. The patient experienced rapid symptom resolution, with the PCV lesion healing within six weeks of starting treatment. This case documents the rare occurrence of plasma cell vulvitis presenting as chronic vulval ulceration, and proposes a treatment regimen worth considering in instances where monotherapy has been ineffective. |
| first_indexed | 2024-04-24T16:26:00Z |
| format | Article |
| id | doaj.art-9ffd00d2009f495f82b3f51b2503fa78 |
| institution | Directory Open Access Journal |
| issn | 2214-9112 |
| language | English |
| last_indexed | 2024-04-24T16:26:00Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Reports in Women's Health |
| spelling | doaj.art-9ffd00d2009f495f82b3f51b2503fa782024-03-31T04:37:26ZengElsevierCase Reports in Women's Health2214-91122024-06-0142e00601Plasma cell vulvitis: A case reportLauren Fisher0Eman Alnaggar1Fiona Stanley Hospital, Perth, WA, Australia; Corresponding author.St John of God Hospital, Murdoch, AustraliaPlasma cell vulvitis (PCV) is a rare inflammatory condition characterised by plasma cell infiltration in the vulva. A woman in her 80s was referred to a specialist gynaecology clinic with chronic, painful vulval ulcers that were non-responsive to topical betamethasone. Following a biopsy confirming PCV, combination therapy was initiated. This included non-pharmacological management, such as promoting aeration and using hypoallergenic clothing and washes, combined with the daily application of clobetasone cream 0.05% and clindamycin cream 0.1%. Additionally, topical estriol 1% was applied twice weekly. The patient experienced rapid symptom resolution, with the PCV lesion healing within six weeks of starting treatment. This case documents the rare occurrence of plasma cell vulvitis presenting as chronic vulval ulceration, and proposes a treatment regimen worth considering in instances where monotherapy has been ineffective.http://www.sciencedirect.com/science/article/pii/S2214911224000225Plasma cell vulvitisZoons vulvitisLichen sclerosisClobetasoneClindamycinEstriol |
| spellingShingle | Lauren Fisher Eman Alnaggar Plasma cell vulvitis: A case report Case Reports in Women's Health Plasma cell vulvitis Zoons vulvitis Lichen sclerosis Clobetasone Clindamycin Estriol |
| title | Plasma cell vulvitis: A case report |
| title_full | Plasma cell vulvitis: A case report |
| title_fullStr | Plasma cell vulvitis: A case report |
| title_full_unstemmed | Plasma cell vulvitis: A case report |
| title_short | Plasma cell vulvitis: A case report |
| title_sort | plasma cell vulvitis a case report |
| topic | Plasma cell vulvitis Zoons vulvitis Lichen sclerosis Clobetasone Clindamycin Estriol |
| url | http://www.sciencedirect.com/science/article/pii/S2214911224000225 |
| work_keys_str_mv | AT laurenfisher plasmacellvulvitisacasereport AT emanalnaggar plasmacellvulvitisacasereport |