Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region
This article summarizes the results of 10 patients (6 men and 4 women) with recurrent non-Hodgkin lymphoma treating with using of rituximab. The diagnosis was confirmed by histological examination with immunohistochemistry. The average patient age was 61.1 years. All patients received from 6 to 8 ch...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2014-07-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/96 |
| _version_ | 1797855555037954048 |
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| author | R. A. Golubenko G. B. Gromov V. I. Vishnevskiy |
| author_facet | R. A. Golubenko G. B. Gromov V. I. Vishnevskiy |
| author_sort | R. A. Golubenko |
| collection | DOAJ |
| description | This article summarizes the results of 10 patients (6 men and 4 women) with recurrent non-Hodgkin lymphoma treating with using of rituximab. The diagnosis was confirmed by histological examination with immunohistochemistry. The average patient age was 61.1 years. All patients received from 6 to 8 chemotherapy courses and 8 rituximab injections, no one patient was withdrawn from therapy. Rituximab treatment in combination with chemotherapy was successful in 7 (70 %) of 10 patients. The major therapy response was a high frequency of CR — 40 %, slightly exceeding the rate of PR — 30 %. Rituximab has been used successfully in the treatment of elderly patients without additional toxicity, which makes it possible to use the drug on an outpatient basis. |
| first_indexed | 2024-04-09T20:25:42Z |
| format | Article |
| id | doaj.art-9ffefe344917410a9526a8c5012efcb3 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:25:42Z |
| publishDate | 2014-07-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-9ffefe344917410a9526a8c5012efcb32023-03-30T20:15:10ZrusABV-pressОнкогематология1818-83462413-40232014-07-016281110.17650/1818-8346-2011-6-2-8-11111Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel regionR. A. Golubenko0G. B. Gromov1V. I. Vishnevskiy2Medical Institute of Orel State University Orel regional hospitalMedical Institute of Orel State UniversityMedical Institute of Orel State UniversityThis article summarizes the results of 10 patients (6 men and 4 women) with recurrent non-Hodgkin lymphoma treating with using of rituximab. The diagnosis was confirmed by histological examination with immunohistochemistry. The average patient age was 61.1 years. All patients received from 6 to 8 chemotherapy courses and 8 rituximab injections, no one patient was withdrawn from therapy. Rituximab treatment in combination with chemotherapy was successful in 7 (70 %) of 10 patients. The major therapy response was a high frequency of CR — 40 %, slightly exceeding the rate of PR — 30 %. Rituximab has been used successfully in the treatment of elderly patients without additional toxicity, which makes it possible to use the drug on an outpatient basis.https://oncohematology.abvpress.ru/ongm/article/view/96non-hodgkin’s lymphomarelapserituximabelderlychemotherapy |
| spellingShingle | R. A. Golubenko G. B. Gromov V. I. Vishnevskiy Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region Онкогематология non-hodgkin’s lymphoma relapse rituximab elderly chemotherapy |
| title | Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region |
| title_full | Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region |
| title_fullStr | Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region |
| title_full_unstemmed | Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region |
| title_short | Experience of using rituximab for recurrent non-Hodgkin lymphoma in elderly patients of the Orel region |
| title_sort | experience of using rituximab for recurrent non hodgkin lymphoma in elderly patients of the orel region |
| topic | non-hodgkin’s lymphoma relapse rituximab elderly chemotherapy |
| url | https://oncohematology.abvpress.ru/ongm/article/view/96 |
| work_keys_str_mv | AT ragolubenko experienceofusingrituximabforrecurrentnonhodgkinlymphomainelderlypatientsoftheorelregion AT gbgromov experienceofusingrituximabforrecurrentnonhodgkinlymphomainelderlypatientsoftheorelregion AT vivishnevskiy experienceofusingrituximabforrecurrentnonhodgkinlymphomainelderlypatientsoftheorelregion |