The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b.

The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b.

K+ channels regulate morphogens to scale adult fins, but little is known about what regulates the channels and how they control morphogen expression. Using the zebrafish pectoral fin bud as a model for early vertebrate fin/limb development, we found that K+ channels also scale this anatomical struct...

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Xehetasun bibliografikoak
Egile Nagusiak: Xiaowen Jiang, Kun Zhao, Yi Sun, Xinyue Song, Chao Yi, Tianlong Xiong, Sen Wang, Yi Yu, Xiduo Chen, Run Liu, Xin Yan, Christopher L Antos
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Public Library of Science (PLoS) 2024-03-01
Saila:PLoS Biology
Sarrera elektronikoa:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002565&type=printable

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