Temozolomide, Simvastatin and Acetylshikonin Combination Induces Mitochondrial-Dependent Apoptosis in GBM Cells, Which Is Regulated by Autophagy

Glioblastoma multiforme (GBM) is one of the deadliest cancers. Temozolomide (TMZ) is the most common chemotherapy used for GBM patients. Recently, combination chemotherapy strategies have had more effective antitumor effects and focus on slowing down the development of chemotherapy resistance. A com...

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Bibliografiska uppgifter
Huvudupphovsmän: Sima Hajiahmadi, Shahrokh Lorzadeh, Rosa Iranpour, Saeed Karima, Masoumeh Rajabibazl, Zahra Shahsavari, Saeid Ghavami
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2023-02-01
Serie:Biology
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Länkar:https://www.mdpi.com/2079-7737/12/2/302