Profile of the bile acid FXR-FGF15 pathway in the glucolipid metabolism disorder of diabetic mice suffering from chronic stress

Profile of the bile acid FXR-FGF15 pathway in the glucolipid metabolism disorder of diabetic mice suffering from chronic stress

Background Imbalances in bile acid (BA) synthesis and metabolism are involved in the onset of diabetes and depression in humans and rodents. However, the role of BAs and the farnesoid X receptor (FXR)/fibroblast growth factor (FGF) 15 signaling pathway in the development of diabetes and depression i...

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Bibliographic Details
Main Authors: Weijia Cai, Canye Li, Zuanjun Su, Jinming Cao, Zhicong Chen, Yitian Chen, Zhijun Guo, Jian Cai, Feng Xu
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
High fed diet
Insulin
Bile acids
FXR
FGF15
Depression
Online Access:https://peerj.com/articles/16407.pdf

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