Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression
Yeast fungi of the genus Trichosporon spp. can colonize the gastrointestinal tract in humans. In recent decades, the pathogenic role of Trichosporon asahii has been increasingly acknowledged especially in the setting of neutropenic patients with hematological malignancies. However, non-neutropenic p...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S221425092300118X |
| _version_ | 1797809862954975232 |
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| author | Juan Luis Quintana Xosse Carreras Andrea S. Salcedo Lourdes Torres Ruíz Manuel Moreno Gonzales Alfonso Del Castillo Mory Hugo Cedrón Cheng Alfredo Chiappe Gonzalez |
| author_facet | Juan Luis Quintana Xosse Carreras Andrea S. Salcedo Lourdes Torres Ruíz Manuel Moreno Gonzales Alfonso Del Castillo Mory Hugo Cedrón Cheng Alfredo Chiappe Gonzalez |
| author_sort | Juan Luis Quintana |
| collection | DOAJ |
| description | Yeast fungi of the genus Trichosporon spp. can colonize the gastrointestinal tract in humans. In recent decades, the pathogenic role of Trichosporon asahii has been increasingly acknowledged especially in the setting of neutropenic patients with hematological malignancies. However, non-neutropenic patients who are immunosuppressed for other reasons are also at risk of developing invasive forms of this mycosis. We present the case of a 62-year-old male, with a history of ulcerative colitis under immunosuppressive treatment and previous exposure to antibiotics for various bacterial infections, who was admitted to the emergency department with a mycotic aneurysm of the abdominal aorta and left common iliac secondary to T. asahii infection. A multidisciplinary approach of the case (both early medical and surgical interventions) allowed the patient’s favorable outcome. The patient was followed for more than two years with no evidence of relapse. We postulate that the diagnosis of invasive Trichosporonosis should be considered in patients with inflammatory bowel disease (IBD) under immunosuppressive treatment and with prior exposure to antibiotics. |
| first_indexed | 2024-03-13T06:59:18Z |
| format | Article |
| id | doaj.art-a00d8d96e94b4ee1ad6fe576a88c67dc |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-03-13T06:59:18Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-a00d8d96e94b4ee1ad6fe576a88c67dc2023-06-07T04:48:17ZengElsevierIDCases2214-25092023-01-0132e01794Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppressionJuan Luis Quintana0Xosse Carreras1Andrea S. Salcedo2Lourdes Torres Ruíz3Manuel Moreno Gonzales4Alfonso Del Castillo Mory5Hugo Cedrón Cheng6Alfredo Chiappe Gonzalez7Clínica Angloamericana, Lima, PeruUniversidad Peruana de Ciencias Aplicadas, Lima, PeruUniversidad Peruana de Ciencias Aplicadas, Lima, PeruServicio de Cirugía Cardíaca, Torácica, Vascular y Endovascular, Clínica Angloamericana, Lima, PeruServicio de Cirugía General, Clínica Angloamericana, Lima, PeruServicio de Urología, Clínica Angloamericana, Lima, PeruServicio de Gastroenterología, Clínica Angloamericana, Lima, Peru; Universidad Peruana Cayetano Heredia, Lima, PeruInstituto de Investigaciones en Ciencias Biomédicas, Universidad Ricardo Palma, Lima, Peru; Servicio de Infectología, Clínica Angloamericana, Lima, Peru; Correspondence to: Av. Del Sur 237, Dpto 203, Urbanization Santa Teresa, District Santiago de Surco, Lima 15039, Peru.Yeast fungi of the genus Trichosporon spp. can colonize the gastrointestinal tract in humans. In recent decades, the pathogenic role of Trichosporon asahii has been increasingly acknowledged especially in the setting of neutropenic patients with hematological malignancies. However, non-neutropenic patients who are immunosuppressed for other reasons are also at risk of developing invasive forms of this mycosis. We present the case of a 62-year-old male, with a history of ulcerative colitis under immunosuppressive treatment and previous exposure to antibiotics for various bacterial infections, who was admitted to the emergency department with a mycotic aneurysm of the abdominal aorta and left common iliac secondary to T. asahii infection. A multidisciplinary approach of the case (both early medical and surgical interventions) allowed the patient’s favorable outcome. The patient was followed for more than two years with no evidence of relapse. We postulate that the diagnosis of invasive Trichosporonosis should be considered in patients with inflammatory bowel disease (IBD) under immunosuppressive treatment and with prior exposure to antibiotics.http://www.sciencedirect.com/science/article/pii/S221425092300118XTrichosporon asahiiMycotic aneurysmUlcerative colitisImmunosuppressive therapy |
| spellingShingle | Juan Luis Quintana Xosse Carreras Andrea S. Salcedo Lourdes Torres Ruíz Manuel Moreno Gonzales Alfonso Del Castillo Mory Hugo Cedrón Cheng Alfredo Chiappe Gonzalez Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression IDCases Trichosporon asahii Mycotic aneurysm Ulcerative colitis Immunosuppressive therapy |
| title | Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression |
| title_full | Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression |
| title_fullStr | Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression |
| title_full_unstemmed | Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression |
| title_short | Mycotic aneurysms due to Trichosporon asahii in a patient with ulcerative colitis under immunosuppression |
| title_sort | mycotic aneurysms due to trichosporon asahii in a patient with ulcerative colitis under immunosuppression |
| topic | Trichosporon asahii Mycotic aneurysm Ulcerative colitis Immunosuppressive therapy |
| url | http://www.sciencedirect.com/science/article/pii/S221425092300118X |
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