Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain

ABSTRACT Following each round of replication, daughter merozoites of the malaria parasite Plasmodium falciparum escape (egress) from the infected host red blood cell (RBC) by rupturing the parasitophorous vacuole membrane (PVM) and the RBC membrane (RBCM). A proteolytic cascade orchestrated by a par...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Sumit Mukherjee, Armiyaw S. Nasamu, Kelly C. Rubiano, Daniel E. Goldberg
स्वरूप: लेख
भाषा:English
प्रकाशित: American Society for Microbiology 2023-04-01
श्रृंखला:mBio
विषय:
ऑनलाइन पहुंच:https://journals.asm.org/doi/10.1128/mbio.00673-23