A Review of Membrane-Based Biosensors for Pathogen Detection

Biosensors are of increasing interest for the detection of bacterial pathogens in many applications such as human, animal and plant health, as well as food and water safety. Membranes and membrane-like structures have been integral part of several pathogen detection platforms. Such structures may se...

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Main Authors: Remko van den Hurk, Stephane Evoy
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/15/6/14045
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author Remko van den Hurk
Stephane Evoy
author_facet Remko van den Hurk
Stephane Evoy
author_sort Remko van den Hurk
collection DOAJ
description Biosensors are of increasing interest for the detection of bacterial pathogens in many applications such as human, animal and plant health, as well as food and water safety. Membranes and membrane-like structures have been integral part of several pathogen detection platforms. Such structures may serve as simple mechanical support, function as a part of the transduction mechanism, may be used to filter out or concentrate pathogens, and may be engineered to specifically house active proteins. This review focuses on membrane materials, their associated biosensing applications, chemical linking procedures, and transduction mechanisms. The sensitivity of membrane biosensors is discussed, and the state of the field is evaluated and summarized.
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spelling doaj.art-a011e9d258594a4db5f5c8eecbcaae622022-12-22T04:24:29ZengMDPI AGSensors1424-82202015-06-01156140451407810.3390/s150614045s150614045A Review of Membrane-Based Biosensors for Pathogen DetectionRemko van den Hurk0Stephane Evoy1Department of Electrical and Computer Engineering, University of Alberta Edmonton, Alberta, AB T6G 2V4, CanadaDepartment of Electrical and Computer Engineering, University of Alberta Edmonton, Alberta, AB T6G 2V4, CanadaBiosensors are of increasing interest for the detection of bacterial pathogens in many applications such as human, animal and plant health, as well as food and water safety. Membranes and membrane-like structures have been integral part of several pathogen detection platforms. Such structures may serve as simple mechanical support, function as a part of the transduction mechanism, may be used to filter out or concentrate pathogens, and may be engineered to specifically house active proteins. This review focuses on membrane materials, their associated biosensing applications, chemical linking procedures, and transduction mechanisms. The sensitivity of membrane biosensors is discussed, and the state of the field is evaluated and summarized.http://www.mdpi.com/1424-8220/15/6/14045biosensorspathogensmembranesbacteriafood safetywater safety
spellingShingle Remko van den Hurk
Stephane Evoy
A Review of Membrane-Based Biosensors for Pathogen Detection
Sensors
biosensors
pathogens
membranes
bacteria
food safety
water safety
title A Review of Membrane-Based Biosensors for Pathogen Detection
title_full A Review of Membrane-Based Biosensors for Pathogen Detection
title_fullStr A Review of Membrane-Based Biosensors for Pathogen Detection
title_full_unstemmed A Review of Membrane-Based Biosensors for Pathogen Detection
title_short A Review of Membrane-Based Biosensors for Pathogen Detection
title_sort review of membrane based biosensors for pathogen detection
topic biosensors
pathogens
membranes
bacteria
food safety
water safety
url http://www.mdpi.com/1424-8220/15/6/14045
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