Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches
The pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases c...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-06-01
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| Series: | Medicines |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2305-6320/4/3/48 |
| _version_ | 1819075095466868736 |
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| author | Ashleigh Anderson Aaron McConville Laura Fanthorpe James Davis |
| author_facet | Ashleigh Anderson Aaron McConville Laura Fanthorpe James Davis |
| author_sort | Ashleigh Anderson |
| collection | DOAJ |
| description | The pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases can be fatal. The drug has been a regular feature of the US National Poison Database Survey over the past decade and continues to pose a risk to children and adults alike. The aim of the review has been to cast a spotlight on the drug and assess why its use remains problematic, how technology could offer more efficacious delivery regimes, and minimise the possibility of accidental or intentional misuse. |
| first_indexed | 2024-12-21T18:19:58Z |
| format | Article |
| id | doaj.art-a01245c3317544a793fa0d48d74fc44c |
| institution | Directory Open Access Journal |
| issn | 2305-6320 |
| language | English |
| last_indexed | 2024-12-21T18:19:58Z |
| publishDate | 2017-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicines |
| spelling | doaj.art-a01245c3317544a793fa0d48d74fc44c2022-12-21T18:54:35ZengMDPI AGMedicines2305-63202017-06-01434810.3390/medicines4030048medicines4030048Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart PatchesAshleigh Anderson0Aaron McConville1Laura Fanthorpe2James Davis3School of Engineering, Ulster University, Jordanstown, Northern Ireland BT37 0QB, UKSchool of Engineering, Ulster University, Jordanstown, Northern Ireland BT37 0QB, UKSchool of Engineering, Ulster University, Jordanstown, Northern Ireland BT37 0QB, UKSchool of Engineering, Ulster University, Jordanstown, Northern Ireland BT37 0QB, UKThe pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases can be fatal. The drug has been a regular feature of the US National Poison Database Survey over the past decade and continues to pose a risk to children and adults alike. The aim of the review has been to cast a spotlight on the drug and assess why its use remains problematic, how technology could offer more efficacious delivery regimes, and minimise the possibility of accidental or intentional misuse.http://www.mdpi.com/2305-6320/4/3/48smart patchesmethyl salicylatetoxicitymicroneedletransdermal |
| spellingShingle | Ashleigh Anderson Aaron McConville Laura Fanthorpe James Davis Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches Medicines smart patches methyl salicylate toxicity microneedle transdermal |
| title | Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches |
| title_full | Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches |
| title_fullStr | Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches |
| title_full_unstemmed | Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches |
| title_short | Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches |
| title_sort | salicylate poisoning potential of topical pain relief agents from age old remedies to engineered smart patches |
| topic | smart patches methyl salicylate toxicity microneedle transdermal |
| url | http://www.mdpi.com/2305-6320/4/3/48 |
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