A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial

Objective . The aim of this study was to determine the feasibility, acceptability, and safety of using moxibustion for treating anorexia and improving quality of life in patients with metastatic cancer. Methods . We conducted a randomized sham-controlled trial of moxibustion. Sixteen patients with m...

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Main Authors: Ju-Hyun Jeon KMD, PhD, Chong-Kwan Cho KMD, PhD, So-Jung Park KMD, PhD, Hwi-Joong Kang KMD, PhD, Kyungmin Kim KMD, In-Chul Jung KMD, PhD, Young-Il Kim KMD, PhD, Suk-Hoon Lee PhD, Hwa-Seung Yoo KMD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/1534735416654762
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author Ju-Hyun Jeon KMD, PhD
Chong-Kwan Cho KMD, PhD
So-Jung Park KMD, PhD
Hwi-Joong Kang KMD, PhD
Kyungmin Kim KMD
In-Chul Jung KMD, PhD
Young-Il Kim KMD, PhD
Suk-Hoon Lee PhD
Hwa-Seung Yoo KMD, PhD
author_facet Ju-Hyun Jeon KMD, PhD
Chong-Kwan Cho KMD, PhD
So-Jung Park KMD, PhD
Hwi-Joong Kang KMD, PhD
Kyungmin Kim KMD
In-Chul Jung KMD, PhD
Young-Il Kim KMD, PhD
Suk-Hoon Lee PhD
Hwa-Seung Yoo KMD, PhD
author_sort Ju-Hyun Jeon KMD, PhD
collection DOAJ
description Objective . The aim of this study was to determine the feasibility, acceptability, and safety of using moxibustion for treating anorexia and improving quality of life in patients with metastatic cancer. Methods . We conducted a randomized sham-controlled trial of moxibustion. Sixteen patients with metastatic cancer were recruited from Daejeon, South Korea. The patients were randomly placed into a true or a sham moxibustion group and received 10 true or sham moxibustion treatments administered to the abdomen (CV12, CV8, CV4) and legs (ST36) over a 2-week period. Outcome measures included interest in participating in the trial, identification of successful recruitment strategies, the appropriateness of eligibility criteria, and compliance with the treatment plan (ie, attendance at treatment sessions). Clinical outcomes included results of the Functional Assessment of Anorexia/Cachexia Therapy (FAACT), answers on the European Organization for Research and Treatment of Cancer 30-item core quality of life (EORTC QLQ-C30) questionnaires, scores on the visual analogue scale (VAS), and the results from blood tests and a safety evaluation. Results . Moxibustion was an acceptable intervention in patients with metastatic cancer. Compliance with the treatment protocol was high, with 11 patients completing all 10 treatments. No serious adverse events related to moxibustion occurred, but 4 patients in the true moxibustion group reported mild rubefaction, which disappeared in a few hours. Conclusion . This study suggests that moxibustion may be safely used to treat anorexia and improve quality of life in patients with metastatic cancer. However, further research is needed to confirm this result.
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spelling doaj.art-a0125f8041bc4eb4a2d732b68fe053252022-12-21T19:43:11ZengSAGE PublishingIntegrative Cancer Therapies1534-73541552-695X2017-03-011610.1177/1534735416654762A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled TrialJu-Hyun Jeon KMD, PhD0Chong-Kwan Cho KMD, PhD1So-Jung Park KMD, PhD2Hwi-Joong Kang KMD, PhD3Kyungmin Kim KMD4In-Chul Jung KMD, PhD5Young-Il Kim KMD, PhD6Suk-Hoon Lee PhD7Hwa-Seung Yoo KMD, PhD8Daejeon Korean Medicine Hospital of Daejeon University, Daejeon, Republic of KoreaDunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of KoreaDunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of KoreaDunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of KoreaDaejeon Korean Medicine Hospital of Daejeon University, Daejeon, Republic of KoreaDunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of KoreaDunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of KoreaChungnam National University, Daejeon, Republic of KoreaDunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of KoreaObjective . The aim of this study was to determine the feasibility, acceptability, and safety of using moxibustion for treating anorexia and improving quality of life in patients with metastatic cancer. Methods . We conducted a randomized sham-controlled trial of moxibustion. Sixteen patients with metastatic cancer were recruited from Daejeon, South Korea. The patients were randomly placed into a true or a sham moxibustion group and received 10 true or sham moxibustion treatments administered to the abdomen (CV12, CV8, CV4) and legs (ST36) over a 2-week period. Outcome measures included interest in participating in the trial, identification of successful recruitment strategies, the appropriateness of eligibility criteria, and compliance with the treatment plan (ie, attendance at treatment sessions). Clinical outcomes included results of the Functional Assessment of Anorexia/Cachexia Therapy (FAACT), answers on the European Organization for Research and Treatment of Cancer 30-item core quality of life (EORTC QLQ-C30) questionnaires, scores on the visual analogue scale (VAS), and the results from blood tests and a safety evaluation. Results . Moxibustion was an acceptable intervention in patients with metastatic cancer. Compliance with the treatment protocol was high, with 11 patients completing all 10 treatments. No serious adverse events related to moxibustion occurred, but 4 patients in the true moxibustion group reported mild rubefaction, which disappeared in a few hours. Conclusion . This study suggests that moxibustion may be safely used to treat anorexia and improve quality of life in patients with metastatic cancer. However, further research is needed to confirm this result.https://doi.org/10.1177/1534735416654762
spellingShingle Ju-Hyun Jeon KMD, PhD
Chong-Kwan Cho KMD, PhD
So-Jung Park KMD, PhD
Hwi-Joong Kang KMD, PhD
Kyungmin Kim KMD
In-Chul Jung KMD, PhD
Young-Il Kim KMD, PhD
Suk-Hoon Lee PhD
Hwa-Seung Yoo KMD, PhD
A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial
Integrative Cancer Therapies
title A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial
title_full A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial
title_fullStr A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial
title_full_unstemmed A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial
title_short A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial
title_sort feasibility study of moxibustion for treating anorexia and improving quality of life in patients with metastatic cancer a randomized sham controlled trial
url https://doi.org/10.1177/1534735416654762
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