Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion
Probiotic extracts have various positive attributes, such as antioxidant, tyrosinase inhibitory, and antimicrobial activity. <i>Lactobacillus curvatus</i> produces bacteriocin, which activates the lipid membrane structure and has potential as a natural preservative for cosmetic emulsions...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/14/24/7571 |
| _version_ | 1797502796361105408 |
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| author | Hyo-Tae Kim Jiseon Lee Yeon-Ji Jo Mi-Jung Choi |
| author_facet | Hyo-Tae Kim Jiseon Lee Yeon-Ji Jo Mi-Jung Choi |
| author_sort | Hyo-Tae Kim |
| collection | DOAJ |
| description | Probiotic extracts have various positive attributes, such as antioxidant, tyrosinase inhibitory, and antimicrobial activity. <i>Lactobacillus curvatus</i> produces bacteriocin, which activates the lipid membrane structure and has potential as a natural preservative for cosmetic emulsions. In this study, <i>L. curvatus</i> extract was encapsulated in liposomes and formulated as an oil-in-water (O/W) emulsion. Radical scavenging activity, tyrosinase inhibition, and challenge tests were conducted to confirm the liposome activity and the activity of the applied lotion emulsion. The liposome-encapsulated extract had a relatively high absolute ζ-potential (52.53 > 35.43), indicating its stability, and 96% permeability, which indicates its potential as an active agent in lotion emulsions. Characterization of emulsions containing the liposomes also indicated a stable state. The liposome-encapsulated extract exhibited a higher radical scavenging activity than samples without the extract and non-encapsulated samples, and the functionality was preserved in the lotion emulsion. The tyrosinase inhibition activity of the lotion emulsion with the liposome-encapsulated extract was similar to that of the non-treated extract. <i>Candida albicans</i> and <i>Aspergillus niger</i> were also inhibited in the challenge test with the lotion emulsions during storage. Collectively, these findings indicate that the liposome-encapsulated extract and the lotion containing the encapsulated extract have potential applicability as natural preservatives. |
| first_indexed | 2024-03-10T03:41:14Z |
| format | Article |
| id | doaj.art-a014011c780c438081cf94bf4e155245 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T03:41:14Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-a014011c780c438081cf94bf4e1552452023-11-23T09:19:45ZengMDPI AGMaterials1996-19442021-12-011424757110.3390/ma14247571Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion LotionHyo-Tae Kim0Jiseon Lee1Yeon-Ji Jo2Mi-Jung Choi3Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaDepartment of Food Processing and Distribution, Gangneung-Wonju National University, Gangwon-do 25457, KoreaDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaProbiotic extracts have various positive attributes, such as antioxidant, tyrosinase inhibitory, and antimicrobial activity. <i>Lactobacillus curvatus</i> produces bacteriocin, which activates the lipid membrane structure and has potential as a natural preservative for cosmetic emulsions. In this study, <i>L. curvatus</i> extract was encapsulated in liposomes and formulated as an oil-in-water (O/W) emulsion. Radical scavenging activity, tyrosinase inhibition, and challenge tests were conducted to confirm the liposome activity and the activity of the applied lotion emulsion. The liposome-encapsulated extract had a relatively high absolute ζ-potential (52.53 > 35.43), indicating its stability, and 96% permeability, which indicates its potential as an active agent in lotion emulsions. Characterization of emulsions containing the liposomes also indicated a stable state. The liposome-encapsulated extract exhibited a higher radical scavenging activity than samples without the extract and non-encapsulated samples, and the functionality was preserved in the lotion emulsion. The tyrosinase inhibition activity of the lotion emulsion with the liposome-encapsulated extract was similar to that of the non-treated extract. <i>Candida albicans</i> and <i>Aspergillus niger</i> were also inhibited in the challenge test with the lotion emulsions during storage. Collectively, these findings indicate that the liposome-encapsulated extract and the lotion containing the encapsulated extract have potential applicability as natural preservatives.https://www.mdpi.com/1996-1944/14/24/7571encapsulationliposomeprobiotics extractcosmetic emulsion lotion |
| spellingShingle | Hyo-Tae Kim Jiseon Lee Yeon-Ji Jo Mi-Jung Choi Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion Materials encapsulation liposome probiotics extract cosmetic emulsion lotion |
| title | Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion |
| title_full | Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion |
| title_fullStr | Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion |
| title_full_unstemmed | Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion |
| title_short | Application of Liposome Encapsulating <i>Lactobacillus curvatus</i> Extract in Cosmetic Emulsion Lotion |
| title_sort | application of liposome encapsulating i lactobacillus curvatus i extract in cosmetic emulsion lotion |
| topic | encapsulation liposome probiotics extract cosmetic emulsion lotion |
| url | https://www.mdpi.com/1996-1944/14/24/7571 |
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