Gestational gigantomastia with fatal outcome
Gigantomastia is a rare disease defined by an extreme and rapid enlargement of the breast, generally bilateral. The majority of cases are reported in pregnant women. Ninety-eight cases of gestational gigantomastia have been identified in electronic databases, and those with fatal outcomes comprised...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University of São Paulo
2021-08-01
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| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | https://www.revistas.usp.br/autopsy/article/view/187744 |
| _version_ | 1819293688535187456 |
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| author | Natalia Rakislova Lucilia Lovane Fabiola Fernandes Emília Gonçalves Quique Bassat Sibone Mocumbi Jaume Ordi Carla Carrilho |
| author_facet | Natalia Rakislova Lucilia Lovane Fabiola Fernandes Emília Gonçalves Quique Bassat Sibone Mocumbi Jaume Ordi Carla Carrilho |
| author_sort | Natalia Rakislova |
| collection | DOAJ |
| description | Gigantomastia is a rare disease defined by an extreme and rapid enlargement of the breast, generally bilateral. The majority of cases are reported in pregnant women. Ninety-eight cases of gestational gigantomastia have been identified in electronic databases, and those with fatal outcomes comprised only 2 cases (2%). Despite its benign nature, it can lead to severe complications and even death. Its etiology has not been fully elucidated, but it has been speculated that a hormonal component may play a role in the pathogenesis. Currently, treatment options are limited, and surgery is gaining importance, but it is often not feasible in low-resource settings. Herein, we describe a case of a 30-year-old HIVpositive female with no relevant past medical history, who died due to the complications of gestational gigantomastia at the Maputo Central Hospital, in Mozambique. |
| first_indexed | 2024-12-24T04:14:24Z |
| format | Article |
| id | doaj.art-a01707647f18459eb629ad2b8f98853c |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-12-24T04:14:24Z |
| publishDate | 2021-08-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-a01707647f18459eb629ad2b8f98853c2022-12-21T17:15:59ZengUniversity of São PauloAutopsy and Case Reports2236-19602021-08-01104Gestational gigantomastia with fatal outcomeNatalia Rakislova0Lucilia Lovane1Fabiola Fernandes2Emília Gonçalves3Quique Bassat4Sibone Mocumbi5Jaume Ordi6 Carla Carrilho7Barcelona Institute for Global health (ISGlobal), Hospital Clínic- Universitat de Barcelona, Barcelona, Spain and Universitat de Barcelona, Hospital Clinic, Department of Pathology, Barcelona, Spain Maputo Central Hospital, Department of Pathology, Maputo, MozambiqueMaputo Central Hospital, Department of Pathology, Maputo, Mozambique and Eduardo Mondlane University, Faculty of Medicine, Department of Pathology, Maputo, MozambiqueEduardo Mondlane University, Faculty of Medicine, Department of Ginecology and Obstetrics, Maputo, Mozambique and Maputo Central Hospital, Department of Ginecology and Obstetrics, Maputo, Mozambique Barcelona Institute for Global health (ISGlobal), Hospital Clínic- Universitat de Barcelona, Barcelona, Spain and Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique and Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain and University of Barcelona, Hospital Sant Joan de Déu, Pediatrics Department, Pediatric Infectious Diseases Unit, Barcelona, Spain and Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, SpainEduardo Mondlane University, Faculty of Medicine, Department of Ginecology and Obstetrics, Maputo, Mozambique and Maputo Central Hospital, Department of Ginecology and Obstetrics, Maputo, MozambiqueBarcelona Institute for Global health (ISGlobal), Hospital Clínic- Universitat de Barcelona, Barcelona, Spain and Universitat de Barcelona, Hospital Clinic, Department of Pathology, Barcelona, SpainMaputo Central Hospital, Department of Pathology, Maputo, Mozambique and Eduardo Mondlane University, Faculty of Medicine, Department of Pathology, Maputo, MozambiqueGigantomastia is a rare disease defined by an extreme and rapid enlargement of the breast, generally bilateral. The majority of cases are reported in pregnant women. Ninety-eight cases of gestational gigantomastia have been identified in electronic databases, and those with fatal outcomes comprised only 2 cases (2%). Despite its benign nature, it can lead to severe complications and even death. Its etiology has not been fully elucidated, but it has been speculated that a hormonal component may play a role in the pathogenesis. Currently, treatment options are limited, and surgery is gaining importance, but it is often not feasible in low-resource settings. Herein, we describe a case of a 30-year-old HIVpositive female with no relevant past medical history, who died due to the complications of gestational gigantomastia at the Maputo Central Hospital, in Mozambique.https://www.revistas.usp.br/autopsy/article/view/187744GigantomastiaBreast DiseasesPregnancyPregnancy ComplicationsHIV |
| spellingShingle | Natalia Rakislova Lucilia Lovane Fabiola Fernandes Emília Gonçalves Quique Bassat Sibone Mocumbi Jaume Ordi Carla Carrilho Gestational gigantomastia with fatal outcome Autopsy and Case Reports Gigantomastia Breast Diseases Pregnancy Pregnancy Complications HIV |
| title | Gestational gigantomastia with fatal outcome |
| title_full | Gestational gigantomastia with fatal outcome |
| title_fullStr | Gestational gigantomastia with fatal outcome |
| title_full_unstemmed | Gestational gigantomastia with fatal outcome |
| title_short | Gestational gigantomastia with fatal outcome |
| title_sort | gestational gigantomastia with fatal outcome |
| topic | Gigantomastia Breast Diseases Pregnancy Pregnancy Complications HIV |
| url | https://www.revistas.usp.br/autopsy/article/view/187744 |
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