Interactions Between the Serotonergic and Other Neurotransmitter Systems in the Basal Ganglia: Role in Parkinson’s Disease and Adverse Effects of L-DOPA

Interactions Between the Serotonergic and Other Neurotransmitter Systems in the Basal Ganglia: Role in Parkinson’s Disease and Adverse Effects of L-DOPA

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. However, other non-dopaminergic neuronal systems such as the serotonergic system are also involved. Serotonergic dysfunction is associated with non-motor symptoms and complications, inc...

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Bibliographic Details
Main Authors: Ana Muñoz, Andrea Lopez-Lopez, Carmen M. Labandeira, Jose L. Labandeira-Garcia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroanatomy
Subjects:
dopamine
dyskinesia
glutamate
Levodopa
Parkinson
serotonin
Online Access:https://www.frontiersin.org/article/10.3389/fnana.2020.00026/full

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