Study of the colonic epithelial-mesenchymal dialogue through establishment of two activated or not mesenchymal cell lines: Activated and resting ones differentially modulate colonocytes in co-culture.

Study of the colonic epithelial-mesenchymal dialogue through establishment of two activated or not mesenchymal cell lines: Activated and resting ones differentially modulate colonocytes in co-culture.

Continuous and rapid renewal of the colonic epithelium is crucial to resist the plethora of luminal deleterious agents. Subepithelial fibroblasts contribute to this turnover by regulating epithelial proliferation and differentiation. However, when intestinal homeostasis is disturbed, fibroblasts can...

Full description

Bibliographic Details
Main Authors: Pascale Plaisancié, Charline Buisson, Edwin Fouché, Pierre Martin, Céline Noirot, Claire Maslo, Jacques Dupuy, Françoise Guéraud, Fabrice Pierre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0273858

Internet

https://doi.org/10.1371/journal.pone.0273858

Similar Items