Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy

Primary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. The incidence of PHP in pregnant women is reported to be 8/100 000 population/year. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and fetus (fetal death, congenital malformations, an...

Full description

Bibliographic Details
Main Authors: Adele J Beck, Venkat M Reddy, Tom Sulkin, Duncan Browne
Format: Article
Language:English
Published: Bioscientifica 2022-09-01
Series:Endocrinology, Diabetes & Metabolism Case Reports
Online Access:https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0203.xml
_version_ 1818480663893901312
author Adele J Beck
Venkat M Reddy
Tom Sulkin
Duncan Browne
author_facet Adele J Beck
Venkat M Reddy
Tom Sulkin
Duncan Browne
author_sort Adele J Beck
collection DOAJ
description Primary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. The incidence of PHP in pregnant women is reported to be 8/100 000 population/year. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and fetus (fetal death, congenital malformations, and neonatal severe hypocalcaemia-induced tetany). However, there is a lack of clear guidance on the management of primary hyperparathyroidism in pregnancy. In this study, we describe the case of a 26-year-old female patient who presented with severe hypercalcaemia secondary to PHP and underwent successful parathyroid adenectomy under local anaesthesia. Primary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. The incidence of PHP in pregnant women is reported to be 8/100 000 population/year. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and fetus (fetal death, congenital malformations, and neonatal severe hypocalcaemia-induced tetany). However, there is a lack of clear guidance on the management of primary hyperparathyroidism in pregnancy. In this study, we describe the case of a 26-year-old female patient who presented with severe hypercalcaemia secondary to PHP and underwent successful parathyroid adenectomy under local anaesthesia.
first_indexed 2024-12-10T11:25:53Z
format Article
id doaj.art-a01a36b9999d49528cf9d2d5be602a7e
institution Directory Open Access Journal
issn 2052-0573
language English
last_indexed 2024-12-10T11:25:53Z
publishDate 2022-09-01
publisher Bioscientifica
record_format Article
series Endocrinology, Diabetes & Metabolism Case Reports
spelling doaj.art-a01a36b9999d49528cf9d2d5be602a7e2022-12-22T01:50:44ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732022-09-01111410.1530/EDM-21-0203Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancyAdele J Beck0Venkat M Reddy1Tom Sulkin2Duncan Browne3Royal Devon University Healthcare NHS Foundation Trust, Exeter, UKRoyal Cornwall Hospitals NHS Trust, Endocrinology and Diabetes Mellitus, Treliske, Truro, UKRoyal Cornwall Hospitals NHS Trust, Endocrinology and Diabetes Mellitus, Treliske, Truro, UKRoyal Cornwall Hospitals NHS Trust, Endocrinology and Diabetes Mellitus, Treliske, Truro, UKPrimary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. The incidence of PHP in pregnant women is reported to be 8/100 000 population/year. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and fetus (fetal death, congenital malformations, and neonatal severe hypocalcaemia-induced tetany). However, there is a lack of clear guidance on the management of primary hyperparathyroidism in pregnancy. In this study, we describe the case of a 26-year-old female patient who presented with severe hypercalcaemia secondary to PHP and underwent successful parathyroid adenectomy under local anaesthesia. Primary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. The incidence of PHP in pregnant women is reported to be 8/100 000 population/year. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and fetus (fetal death, congenital malformations, and neonatal severe hypocalcaemia-induced tetany). However, there is a lack of clear guidance on the management of primary hyperparathyroidism in pregnancy. In this study, we describe the case of a 26-year-old female patient who presented with severe hypercalcaemia secondary to PHP and underwent successful parathyroid adenectomy under local anaesthesia.https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0203.xml
spellingShingle Adele J Beck
Venkat M Reddy
Tom Sulkin
Duncan Browne
Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
Endocrinology, Diabetes & Metabolism Case Reports
title Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
title_full Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
title_fullStr Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
title_full_unstemmed Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
title_short Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
title_sort management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
url https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0203.xml
work_keys_str_mv AT adelejbeck managementofsevereandsymptomaticprimaryhyperparathyroidisminthefirsttrimesterofunplannedpregnancy
AT venkatmreddy managementofsevereandsymptomaticprimaryhyperparathyroidisminthefirsttrimesterofunplannedpregnancy
AT tomsulkin managementofsevereandsymptomaticprimaryhyperparathyroidisminthefirsttrimesterofunplannedpregnancy
AT duncanbrowne managementofsevereandsymptomaticprimaryhyperparathyroidisminthefirsttrimesterofunplannedpregnancy