Clinical and immunological aspects of envenomations by Bothrops snakes

Accidents caused by snakes, especially in tropical and subtropical countries, still constitute a serious public health problem due to the lack of knowledge of health professionals and the precariousness of health systems in the regions where most accidents occur. Snake venoms contain a range of mole...

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Main Authors: KPO Luna, MB da Silva, VRA Pereira
Format: Article
Language:English
Published: SciELO 2011-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200003
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author KPO Luna
MB da Silva
VRA Pereira
author_facet KPO Luna
MB da Silva
VRA Pereira
author_sort KPO Luna
collection DOAJ
description Accidents caused by snakes, especially in tropical and subtropical countries, still constitute a serious public health problem due to the lack of knowledge of health professionals and the precariousness of health systems in the regions where most accidents occur. Snake venoms contain a range of molecules that may provoke local swelling, pain, renal and respiratory insufficiencies. The study of the effects of each molecule on humans can help the development of complementary therapy. Similarly, the knowledge of clinical aspects of envenomations provides a better identification and implementation of appropriate treatment. In addition, to understand Bothrops envenomations and improve the therapeutic strategy, it is necessary to understand and study the role of important inflammatory mediators, particularly nitric oxide (NO), cytokines and the complement system.
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spelling doaj.art-a01bf31ab65644edaa1c0cd9ae03b17d2022-12-21T20:44:20ZengSciELOJournal of Venomous Animals and Toxins including Tropical Diseases1678-91992011-01-0117213014110.1590/S1678-91992011000200003Clinical and immunological aspects of envenomations by Bothrops snakesKPO LunaMB da SilvaVRA PereiraAccidents caused by snakes, especially in tropical and subtropical countries, still constitute a serious public health problem due to the lack of knowledge of health professionals and the precariousness of health systems in the regions where most accidents occur. Snake venoms contain a range of molecules that may provoke local swelling, pain, renal and respiratory insufficiencies. The study of the effects of each molecule on humans can help the development of complementary therapy. Similarly, the knowledge of clinical aspects of envenomations provides a better identification and implementation of appropriate treatment. In addition, to understand Bothrops envenomations and improve the therapeutic strategy, it is necessary to understand and study the role of important inflammatory mediators, particularly nitric oxide (NO), cytokines and the complement system.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200003snakesenvenomationsclinical aspectsimmunology
spellingShingle KPO Luna
MB da Silva
VRA Pereira
Clinical and immunological aspects of envenomations by Bothrops snakes
Journal of Venomous Animals and Toxins including Tropical Diseases
snakes
envenomations
clinical aspects
immunology
title Clinical and immunological aspects of envenomations by Bothrops snakes
title_full Clinical and immunological aspects of envenomations by Bothrops snakes
title_fullStr Clinical and immunological aspects of envenomations by Bothrops snakes
title_full_unstemmed Clinical and immunological aspects of envenomations by Bothrops snakes
title_short Clinical and immunological aspects of envenomations by Bothrops snakes
title_sort clinical and immunological aspects of envenomations by bothrops snakes
topic snakes
envenomations
clinical aspects
immunology
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200003
work_keys_str_mv AT kpoluna clinicalandimmunologicalaspectsofenvenomationsbybothropssnakes
AT mbdasilva clinicalandimmunologicalaspectsofenvenomationsbybothropssnakes
AT vrapereira clinicalandimmunologicalaspectsofenvenomationsbybothropssnakes