Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke

Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke

Abstract Stroke is the most common cause of long-term disability and places a high economic burden on the global healthcare system. Functional outcomes from stroke are largely determined by the extent of ischemic injury, however, there is growing recognition that systemic inflammatory responses also...

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Bibliographic Details
Main Authors: Maria P. Blasco Conesa, Frank W. Blixt, Pedram Peesh, Romeesa Khan, Janelle Korf, Juneyoung Lee, Gayathri Jagadeesan, Alexander Andersohn, Tushar K. Das, Chunfeng Tan, Claudia Di Gesu, Gabriela Delevati Colpo, Jose Félix Moruno-Manchón, Louise D. McCullough, Robert Bryan, Bhanu P. Ganesh
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Neuroinflammation
Subjects:
Histamine
Mast cells
Stabilizer
Gut–brain axis
Neuroinflammation
Cytokines
Online Access:https://doi.org/10.1186/s12974-023-02887-7

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