The Life Sciences Mass Spectrometry Research Unit

The Life Sciences Mass Spectrometry (LSMS) research unit focuses on the development of novel analytical workflows based on innovative mass spectrometric and software tools for the analysis of low molecular weight compounds, peptides and proteins in complex biological matrices. The present...

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Main Authors: Gérard Hopfgartner, Emmanuel Varesio
Format: Article
Language:deu
Published: Swiss Chemical Society 2012-05-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/5219
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author Gérard Hopfgartner
Emmanuel Varesio
author_facet Gérard Hopfgartner
Emmanuel Varesio
author_sort Gérard Hopfgartner
collection DOAJ
description The Life Sciences Mass Spectrometry (LSMS) research unit focuses on the development of novel analytical workflows based on innovative mass spectrometric and software tools for the analysis of low molecular weight compounds, peptides and proteins in complex biological matrices. The present article summarizes some of the recent work of the unit: i) the application of matrix-assisted laser desorption/ionization (MALDI) for mass spectrometry imaging (MSI) of drug of abuse in hair, ii) the use of high resolution mass spectrometry for simultaneous qualitative/quantitative analysis in drug metabolism and metabolomics, and iii) the absolute quantitation of proteins by mass spectrometry using the selected reaction monitoring mode.
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spelling doaj.art-a01cdb5b823d4eafb027d19753eaf0472022-12-21T17:24:42ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242012-05-0166510.2533/chimia.2012.335The Life Sciences Mass Spectrometry Research UnitGérard Hopfgartner0Emmanuel Varesio1School of Pharmaceutical Sciences University of Geneva, University of Lausanne Life Sciences Mass Spectrometry Quai Ernest-Ansermet, 30 CH-1211 Geneva 4, Switzerland. Gerard.Hopfgartner@unige.chSchool of Pharmaceutical Sciences University of Geneva, University of Lausanne Life Sciences Mass Spectrometry Quai Ernest-Ansermet, 30 CH-1211 Geneva 4, Switzerland The Life Sciences Mass Spectrometry (LSMS) research unit focuses on the development of novel analytical workflows based on innovative mass spectrometric and software tools for the analysis of low molecular weight compounds, peptides and proteins in complex biological matrices. The present article summarizes some of the recent work of the unit: i) the application of matrix-assisted laser desorption/ionization (MALDI) for mass spectrometry imaging (MSI) of drug of abuse in hair, ii) the use of high resolution mass spectrometry for simultaneous qualitative/quantitative analysis in drug metabolism and metabolomics, and iii) the absolute quantitation of proteins by mass spectrometry using the selected reaction monitoring mode. https://www.chimia.ch/chimia/article/view/5219Mass spectrometry
spellingShingle Gérard Hopfgartner
Emmanuel Varesio
The Life Sciences Mass Spectrometry Research Unit
CHIMIA
Mass spectrometry
title The Life Sciences Mass Spectrometry Research Unit
title_full The Life Sciences Mass Spectrometry Research Unit
title_fullStr The Life Sciences Mass Spectrometry Research Unit
title_full_unstemmed The Life Sciences Mass Spectrometry Research Unit
title_short The Life Sciences Mass Spectrometry Research Unit
title_sort life sciences mass spectrometry research unit
topic Mass spectrometry
url https://www.chimia.ch/chimia/article/view/5219
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AT emmanuelvaresio thelifesciencesmassspectrometryresearchunit
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AT emmanuelvaresio lifesciencesmassspectrometryresearchunit