ACOT7 promotes retinoblastoma resistance to vincristine by regulating fatty acid metabolism reprogramming

ACOT7 promotes retinoblastoma resistance to vincristine by regulating fatty acid metabolism reprogramming

The rate of vincristine (VCR) resistance in the treatment of retinoblastoma (RB) is relatively high, and the exact role and mechanism of autophagy and fatty acid (FA) metabolism in RB are still unknown. The aim of this study was to elucidate the molecular mechanism by which acyl-CoA thioesterase 7 (...

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Bibliographic Details
Main Authors: Cairui Li, Kaiye Dong, Yanmei Zhuang, Zhaokui Luo, Dong Qiu, Yingjie Luo, Juan Li, Dongxia Xing, Maicong Ma, Weigang Wu, Shuguang Sun
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Retinoblastoma
Vincristine
ACOT7
Fatty acid metabolism reprogramming
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024031876

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