Sarcopenia and Mortality in Critically Ill COVID-19 Patients

COVID-19 can manifest as either asymptomatic or progressing to a severe phase in some patients, which may require hospitalization. These patients may experience dyspnea and hypoxia, leading to the development of acute respiratory distress syndrome. Studies have reported an increased risk of severe s...

Full description

Bibliographic Details
Main Authors: Fatima Al Zahra Yakti, Lana Abusalah, Vijay Ganji
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/14/1/24
_version_ 1827371648600244224
author Fatima Al Zahra Yakti
Lana Abusalah
Vijay Ganji
author_facet Fatima Al Zahra Yakti
Lana Abusalah
Vijay Ganji
author_sort Fatima Al Zahra Yakti
collection DOAJ
description COVID-19 can manifest as either asymptomatic or progressing to a severe phase in some patients, which may require hospitalization. These patients may experience dyspnea and hypoxia, leading to the development of acute respiratory distress syndrome. Studies have reported an increased risk of severe sarcopenia in COVID-19 patients during and after recovery. This narrative review aimed to summarize and synthesize available studies on the association between sarcopenia and mortality in critically ill COVID-19 patients. A total of 22 studies conducted on hospitalized COVID-19 patients were included in this review. Of those, 17 studies reported a direct association, while 5 studies showed no association between sarcopenia and mortality in severe COVID-19 patients. It is important to maintain muscle quality and quantity in defense against COVID-19. The measurement of lean muscle mass should be included in the risk assessment of severely ill COVID-19 patients as part of the therapy plan.
first_indexed 2024-03-08T10:44:32Z
format Article
id doaj.art-a01d630cc5d641a5a6d72d76c0fbe9af
institution Directory Open Access Journal
issn 2075-1729
language English
last_indexed 2024-03-08T10:44:32Z
publishDate 2023-12-01
publisher MDPI AG
record_format Article
series Life
spelling doaj.art-a01d630cc5d641a5a6d72d76c0fbe9af2024-01-26T17:20:26ZengMDPI AGLife2075-17292023-12-011412410.3390/life14010024Sarcopenia and Mortality in Critically Ill COVID-19 PatientsFatima Al Zahra Yakti0Lana Abusalah1Vijay Ganji2Human Nutrition Department, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, QatarHuman Nutrition Department, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, QatarDepartment of Nutrition and Dietetics, School of Health and Human Sciences, Indiana University Indianapolis, 1050 Wishard Blvd., Indianapolis, IN 46202, USACOVID-19 can manifest as either asymptomatic or progressing to a severe phase in some patients, which may require hospitalization. These patients may experience dyspnea and hypoxia, leading to the development of acute respiratory distress syndrome. Studies have reported an increased risk of severe sarcopenia in COVID-19 patients during and after recovery. This narrative review aimed to summarize and synthesize available studies on the association between sarcopenia and mortality in critically ill COVID-19 patients. A total of 22 studies conducted on hospitalized COVID-19 patients were included in this review. Of those, 17 studies reported a direct association, while 5 studies showed no association between sarcopenia and mortality in severe COVID-19 patients. It is important to maintain muscle quality and quantity in defense against COVID-19. The measurement of lean muscle mass should be included in the risk assessment of severely ill COVID-19 patients as part of the therapy plan.https://www.mdpi.com/2075-1729/14/1/24sarcopeniamuscle massCOVID-19coronavirusSARS-CoV-2mortality
spellingShingle Fatima Al Zahra Yakti
Lana Abusalah
Vijay Ganji
Sarcopenia and Mortality in Critically Ill COVID-19 Patients
Life
sarcopenia
muscle mass
COVID-19
coronavirus
SARS-CoV-2
mortality
title Sarcopenia and Mortality in Critically Ill COVID-19 Patients
title_full Sarcopenia and Mortality in Critically Ill COVID-19 Patients
title_fullStr Sarcopenia and Mortality in Critically Ill COVID-19 Patients
title_full_unstemmed Sarcopenia and Mortality in Critically Ill COVID-19 Patients
title_short Sarcopenia and Mortality in Critically Ill COVID-19 Patients
title_sort sarcopenia and mortality in critically ill covid 19 patients
topic sarcopenia
muscle mass
COVID-19
coronavirus
SARS-CoV-2
mortality
url https://www.mdpi.com/2075-1729/14/1/24
work_keys_str_mv AT fatimaalzahrayakti sarcopeniaandmortalityincriticallyillcovid19patients
AT lanaabusalah sarcopeniaandmortalityincriticallyillcovid19patients
AT vijayganji sarcopeniaandmortalityincriticallyillcovid19patients