Role of oxidant injury on macrophage lipoprotein lipase (LPL) production and sensitivity to LPL

We investigated, in the present study, the role of reactive oxygen intermediates (ROI) in the control of macrophage lipoprotein lipase (LPL) secretion. Exposure of murine macrophages to increasing concentrations of hydrogen peroxide (H2O2) resulted in enhanced basal LPL production and mRNA levels. T...

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Bibliographic Details
Main Authors: G Renier, A C Desfaits, A Lambert, R Mikhail
Format: Article
Language:English
Published: Elsevier 1996-04-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520375787