Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy
Subcutaneous fat necrosis (SCFN) of the newborn is an uncommon form of panniculitis that occurs after fetal distress and involves fatty areas during the first weeks of life. This rare disorder is generally self-limiting and undergoes complete regression. However, it can be complicated with a potenti...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Hygeia Press di Corridori Marinella
2016-08-01
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| Series: | Journal of Pediatric and Neonatal Individualized Medicine |
| Subjects: | |
| Online Access: | https://www.jpnim.com/index.php/jpnim/article/view/405 |
| _version_ | 1819074955054153728 |
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| author | Pasqua Anna Quitadamo Antonio Villani Piero Paolo Cristalli Marina Marinelli Anita Riganti Michele Bisceglia Alberto Gatta |
| author_facet | Pasqua Anna Quitadamo Antonio Villani Piero Paolo Cristalli Marina Marinelli Anita Riganti Michele Bisceglia Alberto Gatta |
| author_sort | Pasqua Anna Quitadamo |
| collection | DOAJ |
| description | Subcutaneous fat necrosis (SCFN) of the newborn is an uncommon form of panniculitis that occurs after fetal distress and involves fatty areas during the first weeks of life. This rare disorder is generally self-limiting and undergoes complete regression. However, it can be complicated with a potentially life-threatening hypercalcemia. We report a case of severe hypercalcemia due to SCFN occurring after serious perinatal hypoxic injury, which resolved by intravenous administration of pamidronate. This treatment was rapidly effective and well tolerated. We suggest that pamidronate could be the first-line therapy for severe hypercalcemia in SCFN. |
| first_indexed | 2024-12-21T18:17:44Z |
| format | Article |
| id | doaj.art-a01f5ba2e9c6488f98466e93b0f266bb |
| institution | Directory Open Access Journal |
| issn | 2281-0692 |
| language | English |
| last_indexed | 2024-12-21T18:17:44Z |
| publishDate | 2016-08-01 |
| publisher | Hygeia Press di Corridori Marinella |
| record_format | Article |
| series | Journal of Pediatric and Neonatal Individualized Medicine |
| spelling | doaj.art-a01f5ba2e9c6488f98466e93b0f266bb2022-12-21T18:54:38ZengHygeia Press di Corridori MarinellaJournal of Pediatric and Neonatal Individualized Medicine2281-06922016-08-0152e050226e05022610.7363/405342Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathyPasqua Anna Quitadamo0Antonio Villani1Piero Paolo Cristalli2Marina Marinelli3Anita Riganti4Michele Bisceglia5Alberto Gatta6NICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalyNICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalyNICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalyNICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalyNICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalyNICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalyNICU, Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), ItalySubcutaneous fat necrosis (SCFN) of the newborn is an uncommon form of panniculitis that occurs after fetal distress and involves fatty areas during the first weeks of life. This rare disorder is generally self-limiting and undergoes complete regression. However, it can be complicated with a potentially life-threatening hypercalcemia. We report a case of severe hypercalcemia due to SCFN occurring after serious perinatal hypoxic injury, which resolved by intravenous administration of pamidronate. This treatment was rapidly effective and well tolerated. We suggest that pamidronate could be the first-line therapy for severe hypercalcemia in SCFN.https://www.jpnim.com/index.php/jpnim/article/view/405subcutaneous fat necrosishypercalcemiapamidronatehypoxic-ischemic encephalopathy |
| spellingShingle | Pasqua Anna Quitadamo Antonio Villani Piero Paolo Cristalli Marina Marinelli Anita Riganti Michele Bisceglia Alberto Gatta Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy Journal of Pediatric and Neonatal Individualized Medicine subcutaneous fat necrosis hypercalcemia pamidronate hypoxic-ischemic encephalopathy |
| title | Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy |
| title_full | Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy |
| title_fullStr | Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy |
| title_full_unstemmed | Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy |
| title_short | Important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic-ischemic encephalopathy |
| title_sort | important hypercalcemia due to subcutaneous fat necrosis treated with pamidronate in an infant with severe hypoxic ischemic encephalopathy |
| topic | subcutaneous fat necrosis hypercalcemia pamidronate hypoxic-ischemic encephalopathy |
| url | https://www.jpnim.com/index.php/jpnim/article/view/405 |
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