Characterization of a New Marine Leucine Dehydrogenase from <i>Pseudomonas balearica</i> and Its Application for L-<i>tert</i>-Leucine Production

Characterization of a New Marine Leucine Dehydrogenase from <i>Pseudomonas balearica</i> and Its Application for L-<i>tert</i>-Leucine Production

Leucine dehydrogenase (LeuDH) has emerged as the most promising biocatalyst for L-<i>tert</i>-leucine (L-Tle) production via asymmetric reduction in trimethylpyruvate (TMP). In this study, a new LeuDH named <i>Pb</i>LeuDH from marine <i>Pseudomonas balearica</i> w...

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Bibliographic Details
Main Authors: Zewang Guo, Denghui Chen, Qi Xiong, Miao Liang, Pengfei Li, Zehui Gong, Junzhi Qiu, Liaoyuan Zhang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Catalysts
Subjects:
leucine dehydrogenase
L-<i>tert</i>-leucine
trimethylpyruvate
reductive amination
whole-cell biocatalysis
Online Access:https://www.mdpi.com/2073-4344/12/9/971

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