Myogenic Differential Methylation: Diverse Associations with Chromatin Structure

Myogenic Differential Methylation: Diverse Associations with Chromatin Structure

Employing a new algorithm for identifying differentially methylated regions (DMRs) from reduced representation bisulfite sequencing profiles, we identified 1972 hypermethylated and 3250 hypomethylated myogenic DMRs in a comparison of myoblasts (Mb) and myotubes (Mt) with 16 types of nonmuscle cell c...

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Bibliographic Details
Main Authors:	Sruti Chandra, Carl Baribault, Michelle Lacey, Melanie Ehrlich
Format:	Article
Language:	English
Published:	MDPI AG 2014-06-01
Series:	Biology
Subjects:	DNA methylation histone modification myoblasts DNaseI hypersensitivity differentiation enhancers promoters Polycomb group repression muscle
Online Access:	http://www.mdpi.com/2079-7737/3/2/426

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