Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application
Purpose: To evaluate the effect of applying potassium-iodide (KI) and glutathione (GSH) on silver-diamine fluoride (SDF) induced tooth discoloration as well as their effect on its remineralization potential. Methods: To examine color change, cervical dentinal demineralized cavities were performed...
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2024-03-01
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| Series: | Dentistry 3000 |
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| Online Access: | http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/402 |
| _version_ | 1797278780307275776 |
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| author | Salma Mohammed ElSabaa Ahmed El Banna Dina Ahmed El Refai |
| author_facet | Salma Mohammed ElSabaa Ahmed El Banna Dina Ahmed El Refai |
| author_sort | Salma Mohammed ElSabaa |
| collection | DOAJ |
| description |
Purpose: To evaluate the effect of applying potassium-iodide (KI) and glutathione (GSH) on silver-diamine fluoride (SDF) induced tooth discoloration as well as their effect on its remineralization potential.
Methods: To examine color change, cervical dentinal demineralized cavities were performed mesially and distally in 16 human premolars. Glass-ionomer restoration (GIC) was applied and allocated to four groups I-IV according to the following pre-treatments: No pre-treatment, SDF, SDF+KI, SDF+20%(wt) GSH. Spectrophotometric evaluation of samples at time intervals: 1,7 and 14 days of GIC application. To examine the effect of remineralization, 21 bovine dentin blocks were divided into groups I-III: SDF, SDF + KI, and SDF + GSH. Vickers microhardness was measured, before and after demineralization and after 7 days of treatment.
Results: Spectrophotometric results after 14 days for groups I-IV were:1.29±0.18, 12.24±0.19, 2.19±0.32 and 4.76±0.19 respectively. Groups III and IV showed significant reduction in ΔE compared with group II, although they showed significant increase in ΔE compared with group I (p<0.001). KI showed better management of color changes than GSH. The microhardness test results after treatment application to demineralized dentin for Groups I-III were: 30.81±20.87, 30.59±16.42, 24.69±13.21, respectively. All groups showed significantly increased microhardness of demineralized dentin (P ≤ 0.05), which was comparable to that of Group I.
Conclusion: Application of KI and GSH after SDF significantly minimized color changes without affecting the remineralizing effect of SDF.
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| first_indexed | 2024-03-07T16:14:08Z |
| format | Article |
| id | doaj.art-a028d6076d294f278330c6881e6f6fb4 |
| institution | Directory Open Access Journal |
| issn | 2167-8677 |
| language | English |
| last_indexed | 2024-03-07T16:14:08Z |
| publishDate | 2024-03-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | Dentistry 3000 |
| spelling | doaj.art-a028d6076d294f278330c6881e6f6fb42024-03-04T15:38:37ZengUniversity Library System, University of PittsburghDentistry 30002167-86772024-03-0112110.5195/d3000.2024.402Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride ApplicationSalma Mohammed ElSabaaAhmed El BannaDina Ahmed El Refai Purpose: To evaluate the effect of applying potassium-iodide (KI) and glutathione (GSH) on silver-diamine fluoride (SDF) induced tooth discoloration as well as their effect on its remineralization potential. Methods: To examine color change, cervical dentinal demineralized cavities were performed mesially and distally in 16 human premolars. Glass-ionomer restoration (GIC) was applied and allocated to four groups I-IV according to the following pre-treatments: No pre-treatment, SDF, SDF+KI, SDF+20%(wt) GSH. Spectrophotometric evaluation of samples at time intervals: 1,7 and 14 days of GIC application. To examine the effect of remineralization, 21 bovine dentin blocks were divided into groups I-III: SDF, SDF + KI, and SDF + GSH. Vickers microhardness was measured, before and after demineralization and after 7 days of treatment. Results: Spectrophotometric results after 14 days for groups I-IV were:1.29±0.18, 12.24±0.19, 2.19±0.32 and 4.76±0.19 respectively. Groups III and IV showed significant reduction in ΔE compared with group II, although they showed significant increase in ΔE compared with group I (p<0.001). KI showed better management of color changes than GSH. The microhardness test results after treatment application to demineralized dentin for Groups I-III were: 30.81±20.87, 30.59±16.42, 24.69±13.21, respectively. All groups showed significantly increased microhardness of demineralized dentin (P ≤ 0.05), which was comparable to that of Group I. Conclusion: Application of KI and GSH after SDF significantly minimized color changes without affecting the remineralizing effect of SDF. http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/402Silver diamine fluorideRemineralizationDiscolorationPotassium iodideGlutathione |
| spellingShingle | Salma Mohammed ElSabaa Ahmed El Banna Dina Ahmed El Refai Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application Dentistry 3000 Silver diamine fluoride Remineralization Discoloration Potassium iodide Glutathione |
| title | Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application |
| title_full | Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application |
| title_fullStr | Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application |
| title_full_unstemmed | Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application |
| title_short | Effect of Potassium Iodide and Glutathione on Color Change and Remineralization Potential Induced by Silver Diamine Fluoride Application |
| title_sort | effect of potassium iodide and glutathione on color change and remineralization potential induced by silver diamine fluoride application |
| topic | Silver diamine fluoride Remineralization Discoloration Potassium iodide Glutathione |
| url | http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/402 |
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