Clinical observation of Сhronic granulomatous disease in a 6-year-old child
Chronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis. Clinical manifestations of the disease are recurrent bacterial or fungal infections of the skin, hepatic abscesses, pneumonia, osteomyelitis, sepsis,...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2020-12-01
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| Series: | Детские инфекции (Москва) |
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| Online Access: | https://detinf.elpub.ru/jour/article/view/552 |
| _version_ | 1797881786306396160 |
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| author | G. A. Kharchenko O. G. Kimirilova |
| author_facet | G. A. Kharchenko O. G. Kimirilova |
| author_sort | G. A. Kharchenko |
| collection | DOAJ |
| description | Chronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis. Clinical manifestations of the disease are recurrent bacterial or fungal infections of the skin, hepatic abscesses, pneumonia, osteomyelitis, sepsis, meningitis et al. Most available laboratory method for the diagnosis of CGD is the test of histochemical nitro blue tetrazolium recovery (NBT-test). Allogeneic hematopoietic stem cell transplantation is considered a radical treatment for chronic granulomatous disease. The article presents a clinical observation of the manifestation of chronic granulomatous disease with an unfavorable outcome in a child aged 6 years. |
| first_indexed | 2024-04-10T03:24:38Z |
| format | Article |
| id | doaj.art-a029aca8376240519cb1541127a5802f |
| institution | Directory Open Access Journal |
| issn | 2072-8107 |
| language | Russian |
| last_indexed | 2024-04-10T03:24:38Z |
| publishDate | 2020-12-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj.art-a029aca8376240519cb1541127a5802f2023-03-13T07:28:26ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072020-12-01194697210.22627/2072-8107-2020-19-4-69-72479Clinical observation of Сhronic granulomatous disease in a 6-year-old childG. A. Kharchenko0O. G. Kimirilova1Астраханский государственный медицинский университет Министерства здравоохранения Российской ФедерацииАстраханский государственный медицинский университет Министерства здравоохранения Российской ФедерацииChronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis. Clinical manifestations of the disease are recurrent bacterial or fungal infections of the skin, hepatic abscesses, pneumonia, osteomyelitis, sepsis, meningitis et al. Most available laboratory method for the diagnosis of CGD is the test of histochemical nitro blue tetrazolium recovery (NBT-test). Allogeneic hematopoietic stem cell transplantation is considered a radical treatment for chronic granulomatous disease. The article presents a clinical observation of the manifestation of chronic granulomatous disease with an unfavorable outcome in a child aged 6 years.https://detinf.elpub.ru/jour/article/view/552хроническая гранулематозная болезньдетиклинический случайлечение |
| spellingShingle | G. A. Kharchenko O. G. Kimirilova Clinical observation of Сhronic granulomatous disease in a 6-year-old child Детские инфекции (Москва) хроническая гранулематозная болезнь дети клинический случай лечение |
| title | Clinical observation of Сhronic granulomatous disease in a 6-year-old child |
| title_full | Clinical observation of Сhronic granulomatous disease in a 6-year-old child |
| title_fullStr | Clinical observation of Сhronic granulomatous disease in a 6-year-old child |
| title_full_unstemmed | Clinical observation of Сhronic granulomatous disease in a 6-year-old child |
| title_short | Clinical observation of Сhronic granulomatous disease in a 6-year-old child |
| title_sort | clinical observation of сhronic granulomatous disease in a 6 year old child |
| topic | хроническая гранулематозная болезнь дети клинический случай лечение |
| url | https://detinf.elpub.ru/jour/article/view/552 |
| work_keys_str_mv | AT gakharchenko clinicalobservationofshronicgranulomatousdiseaseina6yearoldchild AT ogkimirilova clinicalobservationofshronicgranulomatousdiseaseina6yearoldchild |