A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii.

A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii.

In RNA silencing, small RNAs produced by the RNase-III Dicer guide Argonaute-like proteins as part of RNA-induced silencing complexes (RISC) to regulate gene expression transcriptionally or post-transcriptionally. Here, we have characterized the RNA silencing machinery and exhaustive small RNAome of...

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Bibliographic Details
Main Authors: Laurence Braun, Dominique Cannella, Philippe Ortet, Mohamed Barakat, Céline F Sautel, Sylvie Kieffer, Jérôme Garin, Olivier Bastien, Olivier Voinnet, Mohamed-Ali Hakimi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2877743?pdf=render

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