Assessment of Substrate Status of Drugs Metabolized by Polymorphic Cytochrome P450 (CYP) 2 Enzymes: An Analysis of a Large-Scale Dataset

Background: The analysis of substrates of polymorphic cytochrome P450 (CYP) enzymes is important information to enable drug–drug interactions (DDIs) analysis and the relevance of pharmacogenetics in this context in large datasets. Our aim was to compare different approaches to assess the substrate p...

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Bibliographische Detailangaben
Hauptverfasser: Jakob Sommer, Justyna Wozniak, Judith Schmitt, Jana Koch, Julia C. Stingl, Katja S. Just
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2024-01-01
Schriftenreihe:Biomedicines
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Online Zugang:https://www.mdpi.com/2227-9059/12/1/161